4-Bromo-2,6-dimethylbenzamide

Base Information

• Chemical Name: 4-Bromo-2,6-dimethylbenzamide
• CAS No.: 132949-41-8
• Molecular Formula: C9H10BrNO
• Molecular Weight: 228.088
• Mol file: 132949-41-8.mol

Synonyms:4-Bromo-2,6-dimethylbenzamide

Chemical Property of 4-Bromo-2,6-dimethylbenzamide

Chemical Property:

• PSA: 43.09000
• LogP: 2.86510

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Bromo-2,6-dimethylbenzamide

There total 1 articles about 4-Bromo-2,6-dimethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-bromo-2,6-dimethylbenzonitrile (5757-66-4) → 4-Bromo-2,6-dimethylbenzamide (132949-41-8)

Guidance literature:

With sodium hydroxide; In methanol; water; for 17h; Heating / reflux;

Reference yield:

4-Bromo-2,6-dimethylbenzamide (132949-41-8) → 4-bromo-2,6-dimethylbenzoic acid (74346-19-3)

Guidance literature:

4-Bromo-2,6-dimethylbenzamide; With nitrosylsulfuric acid; In dichloromethane; water; at 0 - 20 ℃; for 3h;

With water; In dichloromethane; at 0 ℃; for 12h;

upstream raw materials:

4-bromo-2,6-dimethylbenzonitrile

Downstream raw materials:

4-bromo-2,6-dimethylbenzoic acid

Refernces

• 1、 Dell'Erba, Carlo,Mele, Andrea,Novi, Marino,Petrillo, Giovanni,Sancassan, Fernando,Spinelli, Domenico. "On the Nature of Resonance Interactions in Substituted Benzenes. Part 3. A 13C Nuclear Magnetic Resonance Study of Substituent Effects in 4-Substituted Benzamides and Methyl Benzoates in Dimethyl sulphoxide". . p. 2055 - 2058. Retrieved 2007/10/02.