D-erythro-Pentitol, 4,5-anhydro-1,2,3-trideoxy-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-

Base Information

Chemical Name:D-erythro-Pentitol, 4,5-anhydro-1,2,3-trideoxy-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-
CAS No.:170876-73-0
Molecular Formula:C11H21NO3
Molecular Weight:215.28900
Hs Code.:

Synonyms:(2S,3S)-N-Boc-3-amino-1,2-epoxy-4-methylpentane;((S)-2-Methyl-1-(S)-oxiranyl-propyl)-carbamic acid tert-butyl ester;

Suppliers and Price of D-erythro-Pentitol, 4,5-anhydro-1,2,3-trideoxy-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of D-erythro-Pentitol, 4,5-anhydro-1,2,3-trideoxy-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-

Chemical Property:

Melting Point:64-68 °C
Boiling Point:300.1±15.0 °C(Predicted)
PSA：50.86000
Density:1.034±0.06 g/cm3(Predicted)
LogP:2.32540

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of D-erythro-Pentitol, 4,5-anhydro-1,2,3-trideoxy-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-

There total 9 articles about D-erythro-Pentitol, 4,5-anhydro-1,2,3-trideoxy-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 545375-26-6
((1S,2S)-3-Chloro-2-hydroxy-1-isopropyl-propyl)-carbamic acid tert-butyl ester

: 170876-73-0,250165-20-9
tert-butyl (S)-2-methyl-1-((S)-oxiran-2-yl)propylcarbamate

Guidance literature:: With potassium hydroxide; In ethanol; at 20 ℃;
DOI:10.1016/S0960-894X(02)00840-5

Reference yield: 95.0%

: ((1S,2S)-3-Bromo-2-hydroxy-1-isopropyl-propyl)-carbamic acid tert-butyl ester

: 170876-73-0,250165-20-9
tert-butyl (S)-2-methyl-1-((S)-oxiran-2-yl)propylcarbamate

Guidance literature:: With potassium hydroxide; In ethanol; for 1h; Ambient temperature;
DOI:10.1016/00404-0399(50)1087X-

Reference yield:

: (2S,3S)-1-Chloro-3-dibenzylamino-4-methyl-pentan-2-ol; hydrochloride

: 170876-73-0,250165-20-9
tert-butyl (S)-2-methyl-1-((S)-oxiran-2-yl)propylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / H₂, Pd(OH)2/C / methanol

2: 1) Et₃N, 2) KOH / 1) THF, room temperature, 3 h, 2) THF, MeOH, room temperature, 3 h

With palladium dihydroxide; potassium hydroxide; hydrogen; triethylamine; In methanol;
DOI:10.1021/jo960109i