(R)-6-chloro-2-Methyl-1,2,3,4-tetrahydroquinoline

Base Information

Chemical Name:(R)-6-chloro-2-Methyl-1,2,3,4-tetrahydroquinoline
CAS No.:1263000-44-7
Molecular Formula:C10H12ClN
Molecular Weight:181.66200
Hs Code.:2933499090
Mol file:1263000-44-7.mol

Synonyms:2-methyl-6-chloro benzothiazole;;6-Chlor-2-methyl-benzothiazol;;Benzothiazole,6-chloro-2-methyl;;6-chloro-2-methyl-benzothiazole;;2-methyl-6-chloro-1,2,3,4-tetrahydroquinoline;;6-Chlor-2-methyl-benzo<1,3>thiazol;;

Suppliers and Price of (R)-6-chloro-2-Methyl-1,2,3,4-tetrahydroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of (R)-6-chloro-2-Methyl-1,2,3,4-tetrahydroquinoline

Chemical Property:

Boiling Point:292.5±29.0 oC (760 Torr), Calc.*
Flash Point:130.7±24.3 oC, Calc.*
PSA：12.03000
Density:1.106±0.06 g/cm3 (20 oC 760 Torr), Calc.*
LogP:3.22460

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-6-chloro-2-Methyl-1,2,3,4-tetrahydroquinoline

There total 3 articles about (R)-6-chloro-2-Methyl-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 92-46-6
6-chloro-2-methylquinoline

: 1263000-44-7
(R)-6-chloro-2-methyl-1,2,3,4-tetrahydroquinoline

Guidance literature:: With bis(1,5-cyclooctadiene)diiridium(I) dichloride; hydrogen; iodine; (((1R,3S,3'S)-3,3'-diethyl-3H,3'H-1,1'-spirobi[isobenzofuran]-7,7'-diyl)bis(oxy))bis(diphenylphosphane); In tetrahydrofuran; at 20 ℃; for 10h; under 18100.7 Torr; enantioselective reaction; Inert atmosphere;
DOI:10.1039/d0cc03088k

Reference yield:

: 92-46-6
6-chloro-2-methylquinoline

: 1190876-61-9
(S)-6-chloro-2-methyl-1,2,3,4-tetrahydroquinoline

: 1263000-44-7
(R)-6-chloro-2-methyl-1,2,3,4-tetrahydroquinoline

Guidance literature:: With C₃₃H₂₉F₃NO₅PS; C₂₉H₂₅IrN₂O₂S; hydrogen; In o-xylene; at 20 ℃; under 75007.5 Torr; optical yield given as %ee; enantioselective reaction; Inert atmosphere; Autoclave;
DOI:10.1039/c0cc02167a

Reference yield:

: 28328-97-4
6-chloro-2-methyl- 1,2,3,4-tetrahydroquinoline

: 92-46-6
6-chloro-2-methylquinoline

: 1263000-44-7
(R)-6-chloro-2-methyl-1,2,3,4-tetrahydroquinoline

Guidance literature:: With monoamine oxidase from Pseudomonas monteilii ZMU-T₀₁; In aq. buffer; at 37 ℃; pH=7.5; enantioselective reaction; Resolution of racemate;
DOI:10.1002/cctc.201701995