1-METHYL-2-PHENYL-PIPERAZINE DIHYDROCHLORIDE

Base Information

Chemical Name:1-METHYL-2-PHENYL-PIPERAZINE DIHYDROCHLORIDE
CAS No.:1185293-45-1
Molecular Formula:C11H17ClN2
Molecular Weight:212.71908
Hs Code.:
Mol file:1185293-45-1.mol

Synonyms:1-Methyl-2-phenyl-piperazinehydrochloride;Piperazine, 1-Methyl-2-phenyl-, hydrochloride (1:2)

Suppliers and Price of 1-METHYL-2-PHENYL-PIPERAZINE DIHYDROCHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of 1-METHYL-2-PHENYL-PIPERAZINE DIHYDROCHLORIDE

Chemical Property:

PSA：15.27000
LogP:2.33140

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-METHYL-2-PHENYL-PIPERAZINE DIHYDROCHLORIDE

There total 4 articles about 1-METHYL-2-PHENYL-PIPERAZINE DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 1598383-11-9
4-methyl-3-phenyl-piperazine-1-carboxylic acid tert-butyl ester

: 1185293-45-1
1-methyl-2-phenyl-piperazine dihydrochloride

Guidance literature:: With hydrochloric acid diethyl ether; In methanol; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.ejmech.2021.113838

Reference yield:

: 502649-25-4
tert-butyl 4-(3-methoxy-4-(1H-pyrazol-4-yl)benzoyl)-3-phenylpiperazine-1-carboxylate

: 1185293-45-1
1-methyl-2-phenyl-piperazine dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / Inert atmosphere

2: hydrochloric acid diethyl ether / methanol / 20 °C / Inert atmosphere

With hydrochloric acid diethyl ether; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2021.113838

Reference yield:

: 5271-26-1
m-phenylpiperazine

: 1185293-45-1
1-methyl-2-phenyl-piperazine dihydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 24 h / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / Inert atmosphere

3: hydrochloric acid diethyl ether / methanol / 20 °C / Inert atmosphere

With hydrochloric acid diethyl ether; potassium carbonate; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2021.113838