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Technology Process of Betamethasone 21-Propionate

Betamethasone 21-Propionate

Base Information
  • Chemical Name:Betamethasone 21-Propionate
  • CAS No.:75883-07-7
  • Molecular Formula:C25H33FO6
  • Molecular Weight:448.5243
  • Hs Code.:2937220000
  • European Community (EC) Number:641-856-0
  • UNII:91Z2P0I3WH
  • DSSTox Substance ID:DTXSID60226784
  • Nikkaji Number:J464.423I
  • ChEMBL ID:CHEMBL2114050
  • Mol file:75883-07-7.mol
Betamethasone 21-Propionate

Synonyms:Betamethasone 21-Propionate;75883-07-7;UNII-91Z2P0I3WH;91Z2P0I3WH;[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate;Betamethasone-21-Propionate;CHEMBL2114050;SCHEMBL11123086;DTXSID60226784;9-Fluoro-11beta,17-dihydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-21-yl Propanoate (Betamethasone 21-Propionate);Clobetasol Propionate EP Impurity K;AKOS030242944;BETAMETHASONE DIPROPIONATE IMPURITY C;CLOBETASOL PROPIONATE IMPURITY K [EP IMPURITY];Q27271438;9-Fluoro-11beta,17-dihydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-21-yl propanoate;(11beta,16beta)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione;9-FLUORO-11.BETA.,17-DIHYDROXY-16.BETA.-METHYL-21-(PROPIONYLOXY)PREGNA-1,4-DIENE-3,20-DIONE;9.ALPHA.-FLUORO-11.BETA.,17,21-TRIHYDROXY-16.BETA.-METHYLPREGNA-1,4-DIENE-3,20-DIONE 21-PROPIONATE;Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(1-oxopropoxy)-, (11beta,16beta)-

Suppliers and Price of Betamethasone 21-Propionate
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Betamethasone21-Propionate
  • 50mg
  • $ 1355.00
  • Biosynth Carbosynth
  • Betamethasone 21-propionate
  • 10 mg
  • $ 450.00
  • Biosynth Carbosynth
  • Betamethasone 21-propionate
  • 5 mg
  • $ 262.50
  • Biosynth Carbosynth
  • Betamethasone 21-propionate
  • 2 mg
  • $ 140.00
  • Biosynth Carbosynth
  • Betamethasone 21-propionate
  • 50 mg
  • $ 1000.00
  • Biosynth Carbosynth
  • Betamethasone 21-propionate
  • 25 mg
  • $ 750.00
  • AK Scientific
  • Betamethasone21-Propionate
  • 10mg
  • $ 657.00
Total 15 raw suppliers
Chemical Property of Betamethasone 21-Propionate
Chemical Property:
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:223-226 C 
  • Boiling Point:588.715°C at 760 mmHg 
  • PKA:11.97±0.70(Predicted) 
  • Flash Point:309.844°C 
  • PSA：100.90000 
  • Density:1.281g/cm3 
  • LogP:2.85660 
  • Storage Temp.:Refrigerator 
  • Solubility.:Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly) 
  • XLogP3:3.1
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:7
  • Rotatable Bond Count:5
  • Exact Mass:448.22611693
  • Heavy Atom Count:32
  • Complexity:925
Purity/Quality:

99%, *data from raw suppliers

Betamethasone21-Propionate *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Canonical SMILES:CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)O
  • Isomeric SMILES:CCC(=O)OCC(=O)[C@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)O
  • Uses Betamethasone 21-Propionate (Clobetasol Propionate EP Impurity K) is a degradation product of Betamethasone. Glucocorticoid.
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