CEP-32496

Base Information

Chemical Name:CEP-32496
CAS No.:1227678-26-3
Molecular Formula:C24H23ClF3N5O5
Molecular Weight:553.9181296
Hs Code.:
Mol file:1227678-26-3.mol

Synonyms:QCR-56;CS-1116;1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride;

Suppliers and Price of CEP-32496

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
CEP 32496
100mg
$ 1890.00

TRC
CEP-32496Hydrochloride
10mg
$ 385.00

Matrix Scientific
1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride 95%
5g
$ 5994.00

Matrix Scientific
1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride 95%
1g
$ 1998.00

DC Chemicals
CEP-32496hydrochloride >98%
1 g
$ 2500.00

DC Chemicals
CEP-32496hydrochloride >98%
100 mg
$ 650.00

Crysdot
CEP-32496hydrochloride 98+%
5mg
$ 580.00

Chemenu
1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)ureahydrochloride 98%
100mg
$ 730.00

Biosynth Carbosynth
CEP 32496 hydrochloride
10 mg
$ 225.00

Biosynth Carbosynth
CEP 32496 hydrochloride
50 mg
$ 787.50

Total 8 raw suppliers

Chemical Property of CEP-32496

Chemical Property:

PSA：127.35000
LogP:6.14870
Solubility.:Soluble in DMSO

Purity/Quality:

97% ^*data from raw suppliers

CEP 32496 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of CEP-32496

There total 3 articles about CEP-32496 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.6%

: 1188910-76-0
CEP-32496

: 1227678-26-3
1-[3-(6,7-dimethoxy-quinazolin-4-yloxy)-phenyl]-3-[5-(2,2,2-trifluoro-1,1-dimethylethyl)isoxazol-3-yl]urea hydrochloride

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; Isopropyl acetate; isopropyl alcohol;

Reference yield:

: 1188911-77-4
phenyl (5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)carbamate

: 1227678-26-3
1-[3-(6,7-dimethoxy-quinazolin-4-yloxy)-phenyl]-3-[5-(2,2,2-trifluoro-1,1-dimethylethyl)isoxazol-3-yl]urea hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / Isopropyl acetate / 9 h / 70 °C / Inert atmosphere

2: hydrogenchloride / tetrahydrofuran; Isopropyl acetate; isopropyl alcohol

With hydrogenchloride; dmap; In tetrahydrofuran; Isopropyl acetate; isopropyl alcohol;

Reference yield:

: 1188908-37-3
3-(6,7-dimethoxyquinazolin-4-yloxy)-benzenamine

: 1227678-26-3
1-[3-(6,7-dimethoxy-quinazolin-4-yloxy)-phenyl]-3-[5-(2,2,2-trifluoro-1,1-dimethylethyl)isoxazol-3-yl]urea hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / Isopropyl acetate / 9 h / 70 °C / Inert atmosphere

2: hydrogenchloride / tetrahydrofuran; Isopropyl acetate; isopropyl alcohol

With hydrogenchloride; dmap; In tetrahydrofuran; Isopropyl acetate; isopropyl alcohol;