3,4,6-Trifluoro-2-nitroaniline

Base Information

Chemical Name:3,4,6-Trifluoro-2-nitroaniline
CAS No.:361-39-7
Molecular Formula:C6H3F3N2O2
Molecular Weight:192.097
Hs Code.:2921490090
European Community (EC) Number:837-121-0
Mol file:361-39-7.mol

Synonyms:3,4,6-trifluoro-2-nitroaniline;361-39-7;2-Nitro-3,4,6-trifluoroaniline;6-Nitro-2,4,5-trifluoroaniline;3,4,6-Trifluoro-2-nitroaniline;SCHEMBL859789;AMY28389;MFCD21364907;2-Amino-3,5,6-trifluoronitrobenzene;AKOS017529423;AS-60334;CS-0060117;EN300-6734669;A856671

Suppliers and Price of 3,4,6-Trifluoro-2-nitroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3,4,6-Trifluoro-2-nitroaniline 95+%
5g
$ 736.00

Apolloscientific
3,4,6-trifluoro-2-nitroaniline 95%
1g
$ 445.00

Alichem
3,4,6-Trifluoro-2-nitroaniline
5g
$ 720.71

Alichem
3,4,6-Trifluoro-2-nitroaniline
1g
$ 196.02

AK Scientific
3,4,6-trifluoro-2-nitroaniline
100mg
$ 131.60

Total 16 raw suppliers

Chemical Property of 3,4,6-Trifluoro-2-nitroaniline

Chemical Property:

Melting Point:57.3-57.8 °C
Boiling Point:293.7±35.0 °C(Predicted)
PKA:-2.62±0.25(Predicted)
PSA：71.84000
Density:1.653±0.06 g/cm3(Predicted)
LogP:2.69870
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:0
Exact Mass:192.01466183
Heavy Atom Count:13
Complexity:211

Purity/Quality:

99% ^*data from raw suppliers

3,4,6-Trifluoro-2-nitroaniline 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=C(C(=C1F)F)[N+](=O)[O-])N)F

Technology Process of 3,4,6-Trifluoro-2-nitroaniline

There total 4 articles about 3,4,6-Trifluoro-2-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: ethyl (3,4,6-trifluoro-2-nitrophenyl)carbamate

: 361-39-7
3,4,6-trifluoro-2-nitro-aniline

Guidance literature:: With hydrogen bromide; acetic acid; In water; at 150 ℃; for 4h;
DOI:10.1002/ejoc.202100603

Reference yield:

: 366-50-7
N-(2,4,5-trifluorophenyl)acetamide

: 361-39-7
3,4,6-trifluoro-2-nitro-aniline

Guidance literature:: With sulfuric acid; nitric acid; anschliessend mit wss.HCl;
DOI:10.1021/ja01145a055

Reference yield:

: 1997-88-2
ethyl (2,4,5-trifluorophenyl)carbamate

: 361-39-7
3,4,6-trifluoro-2-nitro-aniline

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid; nitric acid / 1.5 h / -30 - 20 °C

2: acetic acid; hydrogen bromide / water / 4 h / 150 °C

With sulfuric acid; hydrogen bromide; nitric acid; acetic acid; In water;
DOI:10.1002/ejoc.202100603