Technology Process of 2-Cyclopentenyl-4-methoxy-1H-indole
There total 7 articles about 2-Cyclopentenyl-4-methoxy-1H-indole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1,1-dimethylethyl 2-(1-cyclopenten-1-yl)-4-methoxy-1H-indole-1-carboxylate;
With
sodium methylate;
In
methanol; toluene;
at 40 - 50 ℃;
for 4h;
Industry scale;
With
water;
In
methanol; toluene;
for 16h;
Industry scale;
- Guidance literature:
-
With
hydrogenchloride; water;
In
acetone;
for 0.166667h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-ethyl-N,N-diisopropylamine / toluene / 40 - 50 °C / Industry scale
1.2: 1.33 h / 39 - 50 °C / Industry scale
2.1: N-cyclohexyl-cyclohexanamine / triphenylphosphine; palladium diacetate / toluene / 0.42 h / 20 °C / Industry scale; Inert atmosphere
2.2: 18.4 - 22.3 °C / Industry scale; Inert atmosphere
3.1: sodium methylate / toluene; methanol / 4 h / 40 - 50 °C / Industry scale
3.2: 16 h / Industry scale
With
sodium methylate; N-ethyl-N,N-diisopropylamine; N-cyclohexyl-cyclohexanamine;
palladium diacetate; triphenylphosphine;
In
methanol; toluene;
2.1: Suziuki Coupling / 2.2: Suzuki Coupling;