6-[4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-4,12,13-trihydroxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione

Base Information

Chemical Name:6-[4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-4,12,13-trihydroxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
CAS No.:118058-74-5
Molecular Formula:C30H55NO10
Molecular Weight:589.767
Hs Code.:
European Community (EC) Number:433-820-6
Mol file:118058-74-5.mol

6-[4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-4,12,13-trihydroxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione

Synonyms:CHEBI:201573;118058-74-5

Suppliers and Price of 6-[4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-4,12,13-trihydroxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
De(cladinosyl)Clarithromycin
250mg
$ 365.00

Medical Isotopes, Inc.
De(cladinosyl)Clarithromycin
100 mg
$ 650.00

Medical Isotopes, Inc.
De(cladinosyl)Clarithromycin
1 g
$ 2200.00

Biosynth Carbosynth
Clarithromycin EP Impurity I
25 mg
$ 1500.00

Biosynth Carbosynth
Clarithromycin EP Impurity I
10 mg
$ 750.00

Biosynth Carbosynth
Clarithromycin EP Impurity I
5 mg
$ 450.00

Biosynth Carbosynth
Clarithromycin EP Impurity I
2 mg
$ 230.00

Biosynth Carbosynth
Clarithromycin EP Impurity I
1 mg
$ 150.00

Total 22 raw suppliers

Chemical Property of 6-[4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-4,12,13-trihydroxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione

Chemical Property:

Melting Point:158-160 °C
Boiling Point:708.6±60.0 °C(Predicted)
PKA:13.10±0.70(Predicted)
PSA：155.22000
Density:1.17±0.1 g/cm3(Predicted)
LogP:1.51450
Storage Temp.:Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:5
Exact Mass:589.38259695
Heavy Atom Count:41
Complexity:887

Purity/Quality:

99%, ^*data from raw suppliers

De(cladinosyl)Clarithromycin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)O)C)OC2C(C(CC(O2)C)N(C)C)O)(C)OC)C)C)O)(C)O
Uses De(cladinosyl) Clarithromycin is an impurity of Clarithromycin (C559750). De(cladinosyl) Clarithromycin showed significantly potent antibacterial activity against community acquired respiratory pathogens. De(cladinosyl) Clarithromycin (Clarithromycin EP Impurity I) is an impurity of Clarithromycin (C559750). De(cladinosyl) Clarithromycin showed significantly potent antibacterial activity against community acquired respiratory pathogens.

Technology Process of 6-[4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-4,12,13-trihydroxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione

There total 7 articles about 6-[4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-4,12,13-trihydroxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%