DL-Alanine-2,3,3,3-d4

Base Information

• Chemical Name: DL-Alanine-2,3,3,3-d4
• CAS No.: 53795-92-9
• Molecular Formula: CD3CD(NH-FMOC)COOH
• Molecular Weight: 473.04
• DSSTox Substance ID: DTXSID30583937
• Nikkaji Number: J2.796.580F
• Mol file: 53795-92-9.mol

Synonyms:DL-Alanine-2,3,3,3-d4;53795-92-9;alanine-2,3,3,3-d4;2-amino-2,3,3,3-tetradeuteriopropanoic acid;DL-Alanine(2,3,3,3-D4);83998-91-8;alanine-d4;2-amino(?H?)propanoic acid;DL-Alanine-2,3,3,3-d?;DTXSID30583937;CHEBI:143534;(2,3,3,3-(2)H4)alanine;2-aminopropionic acid-2,3,3,3-d4;HY-W244382;MS-22724;2-amino(2,3,3,3-(2)H4)propanoic acid;CS-0370496;DL-Alanine-2,3,3,3-d4, 98 atom % D;D98466;(+/-)-2-AMINOPROPIONIC ACID-2,3,3,3-D4

Chemical Property of DL-Alanine-2,3,3,3-d4

Chemical Property:

• Vapor Pressure: 0.0661mmHg at 25°C
• Melting Point: 289oC
• Boiling Point: 212.9oC at 760 mmHg
• Flash Point: 82.6oC
• PSA: 63.32000
• Density: 1.213g/cm3
• LogP: 0.11850
• Storage Temp.: Refrigerator
• Solubility.: Aqueous Acid (Slightly), Water (Slightly)
• XLogP3: -3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 93.072785450
• Heavy Atom Count: 6
• Complexity: 61.8

Purity/Quality:

99%min. ^*data from raw suppliers

Alanine-d4 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)O)N
• Isomeric SMILES: [2H]C([2H])([2H])C([2H])(C(=O)O)N
• Uses: Alanine-d4 is the isotope labelled analog of Alanine (A481400). Alanine is an amino acid that occurs naturally in nature. It is a functional component in the alanine cycle which regulates the level of alanine aminotransferases which can be used as a diagnostic tool to predict type II diabetes.

Technology Process of DL-Alanine-2,3,3,3-d4

There total 1 articles about DL-Alanine-2,3,3,3-d4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyruvic-d3 acid (68006-61-1) → alanine-2,3,3,3-d4 (53795-92-9,53795-94-1)

Guidance literature:

With water-d2; transaminase;

Reference yield:

alanine-2,3,3,3-d4 (53795-92-9,53795-94-1) → 2-aminopropan-1,1,2,3,3,3-d6-1-ol (352438-84-7)

Guidance literature:

With lithium aluminium deuteride; In tetrahydrofuran; at 0 ℃; for 3h; Reflux;

upstream raw materials:

pyruvic-d3 acid

Downstream raw materials:

2-aminopropan-1,1,2,3,3,3-d6-1-ol

Refernces