5H-thieno[2,3-c]pyran-3-carboxylic acid, 2-amino-4,7-dihyd

Base Information

• Chemical Name: 5H-thieno[2,3-c]pyran-3-carboxylic acid, 2-amino-4,7-dihyd
• CAS No.: 923010-75-7
• Molecular Formula: C8H9NO3S
• Molecular Weight: 199.23
• Hs Code.: 2934999090
• Mol file: 923010-75-7.mol

Synonyms:2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid;2-amino-4H,5H,7H-thieno[2,3-c]pyran-3-carboxylic acid;

Chemical Property of 5H-thieno[2,3-c]pyran-3-carboxylic acid, 2-amino-4,7-dihyd

Chemical Property:

• PSA: 100.79000
• LogP: 1.68240

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5H-thieno[2,3-c]pyran-3-carboxylic acid, 2-amino-4,7-dihyd

There total 1 articles about 5H-thieno[2,3-c]pyran-3-carboxylic acid, 2-amino-4,7-dihyd which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid ethyl ester (117642-16-7) → 2-amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid ester (923010-75-7)

Guidance literature:

With water; In ethanol; at 70 ℃; for 4h; Alkaline conditions;

DOI:10.1080/10286020.2018.1540599

Reference yield: 56.0%

2-amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid ester (923010-75-7) + benzylamine (100-46-9) → 2-amino-5-benzylcarbamoyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid tert-butyl ester (330192-70-6)

Guidance literature:

With 2,6-dimethylpyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 72h;

upstream raw materials:

2-amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid ethyl ester

Downstream raw materials:

2-amino-5-benzylcarbamoyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid tert-butyl ester