N-[1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-benzamide

Base Information

Chemical Name:N-[1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-benzamide
CAS No.:325683-91-8
Molecular Formula:C36H33N3O7
Molecular Weight:619.66
Hs Code.:
Mol file:325683-91-8.mol

Synonyms:4"'-dimethoxytriphenyl)methyl]-α-L-threofuranosyl}cytosine";N4-benzoyl-1-{3'-O-[(4;N-(1-(4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide;

Suppliers and Price of N-[1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(1-(4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide 95+%
1g
$ 1226.00

Chemenu
N-(1-(4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide 95%
1g
$ 1147.00

Alichem
N-(1-(4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide
1g
$ 1083.50

Total 7 raw suppliers

Chemical Property of N-[1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-benzamide

Chemical Property:

PSA：121.14000
Density:1.28±0.1 g/cm3 (20 oC 760 Torr)
LogP:4.85280

Purity/Quality:

97% ^*data from raw suppliers

N-(1-(4-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-[1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-benzamide

There total 7 articles about N-[1-[(2R,3R,4S)-4-[Bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 325683-86-1
N⁴-benzoyl-1-(α-L-threofuranosyl)cytosine

: N⁴-benzoyl-1-{2'-O-[(4,4'-dimethoxytriphenyl)methyl]-α-L-threofuranosyl}cytosine

: 325683-91-8
N⁴-benzoyl-1-{3'-O-[(4,4'-dimethoxytriphenyl)methyl]-α-L-threofuranosyl}cytosine

Guidance literature:: With 2,6-dimethylpyridine; silver trifluoromethanesulfonate; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1002/hlca.200290000

Reference yield:

: N⁴-benzoyl-1-(2′-O-benzoyl-α-L-threofuranosyl)cytosine

: 325683-91-8
N⁴-benzoyl-1-{3'-O-[(4,4'-dimethoxytriphenyl)methyl]-α-L-threofuranosyl}cytosine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; dmap / 16 h / 80 °C / Inert atmosphere

2: sodium hydroxide; water / tetrahydrofuran; methanol / 0.33 h / 0 °C

With pyridine; dmap; water; sodium hydroxide; In tetrahydrofuran; methanol;
DOI:10.1021/acs.joc.5b02768