Technology Process of 2-(Bromomethyl)-4-fluoropyridine
There total 1 articles about 2-(Bromomethyl)-4-fluoropyridine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile);
In
tetrachloromethane;
at 80 ℃;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate / acetonitrile / 1.5 h / 80 °C
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 100 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; potassium carbonate;
In
1,4-dioxane; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / acetonitrile / 1.5 h / 80 °C
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 100 °C / Inert atmosphere
3: potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 10 h / 100 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; potassium carbonate;
In
1,4-dioxane; acetonitrile;
