(3S,4R)-Methyl (3,4- Isopropylidenedooxypyrrolidin-2-ylidene) acetate

Base Information

Chemical Name:(3S,4R)-Methyl (3,4- Isopropylidenedooxypyrrolidin-2-ylidene) acetate
CAS No.:95456-60-3
Molecular Formula:C₁₀H₁₅NO₄
Molecular Weight:213.233
Hs Code.:
Mol file:95456-60-3.mol

Synonyms:(3S,4R)-METHYL (3,4- ISOPROPYLIDENEDOOXYPYRROLIDIN-2-YLIDENE) ACETATE;4H-1,3-Dioxolo[4,5-c]pyrrole, D-erythro-hex-2-enonic acid deriv.;D-erythro-Hex-2-enonic acid, 2,3,6-trideoxy-3,6-imino-4,5-O-(1-methylethylidene)-, methyl ester, (Z)-;

Suppliers and Price of (3S,4R)-Methyl (3,4- Isopropylidenedooxypyrrolidin-2-ylidene) acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of (3S,4R)-Methyl (3,4- Isopropylidenedooxypyrrolidin-2-ylidene) acetate

Chemical Property:

Boiling Point:319.8±42.0 °C (760 mmHg)
PSA：56.79000
Density:1.206±0.06 g/cm3 (20 °C, 760 mmHg)
LogP:0.49540

Purity/Quality:: 99.3% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3S,4R)-Methyl (3,4- Isopropylidenedooxypyrrolidin-2-ylidene) acetate

There total 8 articles about (3S,4R)-Methyl (3,4- Isopropylidenedooxypyrrolidin-2-ylidene) acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 95456-67-0
methyl (Z)-3-amino-2,3-dideoxy-4,5-O-isopropylidene-6-O-methylsulphonyl-D-erythro-hex-2-enonate

: 1042692-11-4,95456-60-3
(3S,4R)-methyl (Z)-(3,4-O-isopropylidenedioxypyrrolidin-2-ylidene)acetate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; for 48h; Ambient temperature;
DOI:10.1039/P19870002377

Reference yield: 80.0%

: 95456-67-0,95456-68-1
methyl (E)-3-amino-2,3-dideoxy-4,5-O-isopropylidene-6-O-methylsulphonyl-D-erythro-hex-2-enonate

: 95456-61-4,95456-60-3
(3S,4R)-methyl (E)-(3,4-O-isopropylidenedioxypyrrolidin-2-ylidene)acetate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; for 48h; Ambient temperature;
DOI:10.1039/P19870002377

Reference yield:

: 95456-66-9
(2S,3R)-2,3-O-isopropylidene-4-O-methanesulfonylerythronitrile

: 95456-61-4,95456-60-3
(3S,4R)-methyl (E)-(3,4-O-isopropylidenedioxypyrrolidin-2-ylidene)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: activated Zn / tetrahydrofuran / Heating

2: DBU / CH₂Cl₂ / 24 h / Ambient temperature

With 1,8-diazabicyclo[5.4.0]undec-7-ene; zinc; In tetrahydrofuran; dichloromethane;
DOI:10.1039/c39840001299