3-(1-Bromo-8-chloroimidazo[1,5-A]pyrazin-3-YL)cyclobutanone

Base Information

Chemical Name:3-(1-Bromo-8-chloroimidazo[1,5-A]pyrazin-3-YL)cyclobutanone
CAS No.:936901-73-4
Molecular Formula:C10H7BrClN3O
Molecular Weight:300.542
Hs Code.:
European Community (EC) Number:632-645-4
DSSTox Substance ID:DTXSID201189845
Mol file:936901-73-4.mol

Synonyms:936901-73-4;3-(1-BROMO-8-CHLOROIMIDAZO[1,5-A]PYRAZIN-3-YL)CYCLOBUTANONE;3-(1-Bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclobutan-1-one;3-{1-BROMO-8-CHLOROIMIDAZO[1,5-A]PYRAZIN-3-YL}CYCLOBUTAN-1-ONE;SCHEMBL594589;SPFGLRKIXCHBPT-UHFFFAOYSA-N;DTXSID201189845;3-(1-Bromo-8-chloro-imidazo[1,5-a]pyrazin-3-yl)-cyclobutanone;Cyclobutanone, 3-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)-;AKOS027256111;SB17809;AS-70859;CS-0035661;3-(1-Bromo-8-chloroimidazo[1,5-alpha]pyrazin-3-yl)cyclobutanone

Suppliers and Price of 3-(1-Bromo-8-chloroimidazo[1,5-A]pyrazin-3-YL)cyclobutanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(1-Bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclobutanone 95+%
1g
$ 918.00

Chemenu
3-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclobutan-1-one 95%
1g
$ 866.00

Alichem
3-(1-Bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclobutanone
250mg
$ 405.60

Alichem
3-(1-Bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclobutanone
1g
$ 1023.75

AK Scientific
3-(1-Bromo-8-Chloroimidazo[1,5-A]Pyrazin-3-Yl)Cyclobutanone
5g
$ 2793.20

Total 8 raw suppliers

Chemical Property of 3-(1-Bromo-8-chloroimidazo[1,5-A]pyrazin-3-YL)cyclobutanone

Chemical Property:

PSA：47.26000
Density:2.03±0.1 g/cm3 (20 °C, 760 mmHg)
LogP:2.59170
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:298.94610
Heavy Atom Count:16
Complexity:308

Purity/Quality:

97% ^*data from raw suppliers

3-(1-Bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclobutanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CC1=O)C2=NC(=C3N2C=CN=C3Cl)Br

Technology Process of 3-(1-Bromo-8-chloroimidazo[1,5-A]pyrazin-3-YL)cyclobutanone

There total 5 articles about 3-(1-Bromo-8-chloroimidazo[1,5-A]pyrazin-3-YL)cyclobutanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 936901-72-3
3-(8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclobutanone

: 936901-73-4
3-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclobutanone

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 0 ℃; for 0.25h; Inert atmosphere;
DOI:10.1021/ml400160a

Reference yield:

: 939412-81-4
3-oxocyclobutanecarboxylic acid 2,5-dioxopyrrolidin-1-yl ester

: 936901-73-4
3-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclobutanone

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydrogencarbonate / water; tetrahydrofuran / 1.5 h / 20 °C

2: trichlorophosphate / N,N-dimethyl-formamide / 0.75 h / 10 - 20 °C

3: N-Bromosuccinimide / N,N-dimethyl-formamide / 0.25 h / 0 °C / Inert atmosphere

With N-Bromosuccinimide; sodium hydrogencarbonate; trichlorophosphate; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1021/ml400160a

Reference yield:

: C₁₄H₁₃ClN₄O₄

: 936901-73-4
3-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclobutanone

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate / N,N-dimethyl-formamide / 0.75 h / 10 - 20 °C

2: N-Bromosuccinimide / N,N-dimethyl-formamide / 0.25 h / 0 °C / Inert atmosphere

With N-Bromosuccinimide; trichlorophosphate; In N,N-dimethyl-formamide;
DOI:10.1021/ml400160a