N-(Allyloxy)-2-nitrobenzenesulfonamide

Base Information

• Chemical Name: N-(Allyloxy)-2-nitrobenzenesulfonamide
• CAS No.: 359442-67-4
• Molecular Formula: C9H10N2 O5 S
• Molecular Weight: 258.25
• Hs Code.: 2935009090
• Mol file: 359442-67-4.mol

Synonyms:2-nitro-N-prop-2-enoxybenzenesulfonamide;

Chemical Property of N-(Allyloxy)-2-nitrobenzenesulfonamide

Chemical Property:

• Boiling Point: 394.9±52.0 °C(Predicted)
• PKA: 5.73±0.40(Predicted)
• PSA: 109.60000
• Density: 1.385±0.06 g/cm3(Predicted)
• LogP: 2.98560
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

N-(Allyloxy)-2-nitrobenzenesulfonamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(Allyloxy)-2-nitrobenzenesulfonamide

There total 1 articles about N-(Allyloxy)-2-nitrobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

O-allylhydroxylamine hydrochloride (38945-21-0) + 2-Nitrobenzenesulfonyl chloride (1694-92-4) → N-(2-Nitrophenylsulfonyl)-O-(2-propenyl)hydroxylamine (359442-67-4)

Guidance literature:

With pyridine; at 0 ℃; for 1h;

Reference yield: 92.0%

1-benzyl-5-(tetrazol-2-yl)-3,6-dihydro-2H-pyridin-3-ol + N-(2-Nitrophenylsulfonyl)-O-(2-propenyl)hydroxylamine (359442-67-4) → N-allyloxy-N-[1-benzyl-5-(tetrazol-2-yl)-3,6-dihydro-2H-pyridin-3-yl]-2-nitrobenzenesulfonamide

Guidance literature:

With triphenylphosphine; In toluene; at 0 - 20 ℃; for 4h; Inert atmosphere;

Reference yield: 88.0%

(S)-tert-butyl 2-((tert-butyldimethylsilyloxy)methyl)-5-hydroxy-4-(methoxymethyl)-5,6-dihydropyridine-1(2H)-carboxylate + N-(2-Nitrophenylsulfonyl)-O-(2-propenyl)hydroxylamine (359442-67-4) → (S)-tert-butyl 5-(N-(allyloxy)-2-nitrophenylsulfonamido)-2-((tert-butyldimethylsilyloxy)methyl)-4-(methoxymethyl)-5,6-dihydropyridine-1(2H)-carboxylate

Guidance literature:

With diisopropyl (E)-azodicarboxylate; triphenylphosphine; In toluene; at 18 - 25 ℃;

upstream raw materials:

O-allylhydroxylamine hydrochloride

2-Nitrobenzenesulfonyl chloride

Refernces

• 1、 -. "BETA-LACTAMASE INHIBITOR COMPOUNDS". Page/Page column 107; 108. . Retrieved 2018/04/13.
• 2、 Reddy, Poreddy Amruta,Schall, Otto F.,Wheatley, James R.,Rosik, Leonard O.,McClurg, Joseph P.,Marshall, Garland R.,Slomczynska, Urszula. "O-Protected N-(2-Nitrophenylsulfonyl)hydroxylamines: Novel Reagents for the Synthesis of Hydroxamates". . p. 1086 - 1092. Retrieved 2007/10/03.