FMOC-ARG(PBF)-OPFP

Base Information

Chemical Name:FMOC-ARG(PBF)-OPFP
CAS No.:7004-12-8
Molecular Formula:C₆H₁₄N₄O₂
Molecular Weight:174.203
Hs Code.:
Mol file:7004-12-8.mol

Synonyms:FMOC-L-ARG(PBF)-OPFP;FMOC-ARGININE(PBF)-OPFP;FMOC-N-OMEGA-(2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL)-L-ARGININE PENTAFLUOROPHENYL ESTER;N-ALPHA-FMOC-N-2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL-L-ARGININE PENTAFLUORPHENYL ESTER;N-ALPHA-FMOC-NG-(2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL)-L-ARGININE PENTAFLUOROPHENYL ESTER;ARGININE;5-Guanidino-2-aminopentanoic acid

Suppliers and Price of FMOC-ARG(PBF)-OPFP

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Arginine European Pharmacopoeia (EP) Reference Standard
$ 190.00

Total 15 raw suppliers

Chemical Property of FMOC-ARG(PBF)-OPFP

Chemical Property:

Melting Point:222 °C
Boiling Point:409.14 °C
PKA:1.82(at 25℃)
Flash Point:201.241 °C
PSA：125.22000
Density:1.467 g/cm3
LogP:0.55280
Storage Temp.:-15°C

Purity/Quality:

99% ,98%,Electron Grade , ^*data from raw suppliers

Arginine European Pharmacopoeia (EP) Reference Standard ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description Arginine (abbreviated as Arg or R) is an α-amino acid. It was first isolated in 1886 . The L - form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that code for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual. Preterm infants are unable to synthesize or create arginine internally, making the amino acid nutritionally essential for them. There are some conditions that put an increased demand on the body for the synthesis of L-arginine, including surgical or other trauma, sepsis and burns . Arginine was first isolated from a lupin seedling extract in 1886 by the Swiss chemist Ernst Schultze.In general, most people do not need to take arginine supplements because the body usually produces enough.
Physical properties The amino acid side-chain of arginine consists of a 3-carbon aliphatic straight chain, the distal end of which is capped by a complex guanidinium group.With a pKa of 12.48, the guanidinium group is positively charged in neutral, acidic and even most basic environments, and thus imparts basic chemical properties to arginine. Because of the conjugation between the double bond and the nitrogen lone pairs, the positive charge is delocalized, enabling the formation of multiple H-bonds.
Uses Lung inflammation and asthma Inhalation of L-arginine can increase lung inflammation and worsen asthma. Growth hormone Intravenously-administered arginine stimulates the secretion of growth hormone , and is used in growth hormone stimulation tests. Two studies have found that oral L-arginine supplementation is also effective at increasing resting GH levels. The first study found that oral preparations of L-arginine are effective at increasing growth hormone levels. In fact, the 9g dose resulted in mean peak GH levels of 6.4 (+/- 1.3) microg / L versus placebo levels of 2.9 (+/- 0.7). MELAS syndromeSeveral trials delved into effects of L-arginine in MELAS syndrome, a mitochondrial disease. SepsisCellular arginine biosynthetic capacity determined by activity of argininosuccinate synthetase (AS) is induced by the same mediators of septic response — endotoxin and cytokines — that induce nitric oxide synthase (NOS), the enzyme responsible for nitric oxide synthesis. Malate saltThe malate salt of arginine can also be used during the treatment of alcoholic hepatitis and advanced cirrhosis. Pre-eclampsiaA preliminary study of supplementation with L-arginine and antioxidant vitamins showed that this combination may help to combat abnormally high blood pressure during high risk pregnancies. HypertensionIntravenous infusion of arginine reduces blood pressure in patients with hypertension as well as normal subjects.A recent meta-analysis showed that L-arginine reduces blood pressure with pooled estimates of 5.4 / 2.7 mmHg for SBP / DBP. Erectile dysfunctionArginine taken in combination with proanthocyanidins or yohimbine, has also been used as a treatment for erectile dysfunction. AnxietyDietary supplementation of L-arginine taken in combination with L-lysine has been shown potentially useful in treating people subjected to high levels of mental stress and anxiety, in a doubleblind, placebo controlled and randomized study, involving 108 Japanese adults. Trait anxiety and state anxiety induced by cognitive stress battery was significantly reduced, and basal levels of the stress hormone cortisol were decreased. The study was funded by Ajinomoto, Co. Inc., an industrial manufacturer of lysine and arginine. Ammonia detoxicant; diagnostic aid (pituitary function determination). arginine is also known as l-arginine. This is an amino acid with antistatic, masking, hair-and skin-conditioning properties. Arginine is a nonessential amino acid that exists as white crystals or powder. it is soluble in water. it is used to improve the biological quality of the total protein in a food which contains naturally occur- ring primarily intact proteins and as a nutrient and dietary supplement.
Biological Functions Arginine plays an important role in cell division, the healing of wounds, removing ammonia from the body, immune function, and the release of hormones. The benefits and functions attributed to oral supplementation of L-arginine include: Precursor for the synthesis of nitric oxide (NO) Reduces healing time of injuries (particularly bone) Quickens repair time of damaged tissue Helps decrease blood pressure in clinical hypertensive subjects.

Technology Process of FMOC-ARG(PBF)-OPFP

There total 5 articles about FMOC-ARG(PBF)-OPFP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

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