(-)-Benzotetramisole

Base Information

Chemical Name:(-)-Benzotetramisole
CAS No.:950194-37-3
Molecular Formula:C15H12N2S
Molecular Weight:252.34
Hs Code.:2934999090
ChEMBL ID:CHEMBL1602198
DSSTox Substance ID:DTXSID50589931
Nikkaji Number:J2.498.474E
Wikidata:Q82483568
Mol file:950194-37-3.mol

Synonyms:(-)-Benzotetramisole;950194-37-3;(S)-2-Phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole;(-)-BTM;MLS002206350;(2S)-2-phenyl-1,2-dihydroimidazo[2,1-b][1,3]benzothiazole;SMR001295168;(2S)-2-Phenyl-2,3-dihydroimidazo[2,1-b][1,3]benzothiazole;Imidazo[2,1-b]benzothiazole, 2,3-dihydro-2-phenyl-, (2S)-;(2S)-2,3-Dihydro-2-phenylimidazo[2,1-b]benzothiazole;(4S)-4-PHENYL-7-THIA-2,5-DIAZATRICYCLO[6.4.0.0(2),?]DODECA-1(12),5,8,10-TETRAENE;MFCD15072149;CHEMBL1602198;SCHEMBL25226606;DTXSID50589931;cid_17747785;YGCWPCVAVSIFLO-GFCCVEGCSA-N;BDBM115080;HMS2210M19;AKOS025147094;CS-W012615;AS-69584;B3549;(4S)-4-phenyl-7-thia-2,5-diazatricyclo[6.4.0.0(2),?]dodeca-1(8),5,9,11-tetraene

Suppliers and Price of (-)-Benzotetramisole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(-)-Benzotetramisole
10mg
$ 45.00

TCI Chemical
(-)-Benzotetramisole >98.0%(GC)
1g
$ 195.00

SynQuest Laboratories
(2S)-2-Phenyl-2,3-dihydroimidazo[2,1-b][1,3]benzothiazole 98.0%
1 g
$ 120.00

Matrix Scientific
Imidazo[2,1-b]benzothiazole 2,3-dihydro-2-phenyl-(2S)-
5g
$ 540.00

Matrix Scientific
Imidazo[2,1-b]benzothiazole 2,3-dihydro-2-phenyl-(2S)-
10g
$ 864.00

Matrix Scientific
Imidazo[2,1-b]benzothiazole 2,3-dihydro-2-phenyl-(2S)-
1g
$ 191.00

Crysdot
(S)-2-Phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole 95+%
5g
$ 456.00

Chemenu
Imidazo[2,1-b]benzothiazole,2,3-dihydro-2-phenyl-,(2S)- 95%
5g
$ 427.00

Biosynth Carbosynth
(-)-Benzotetramisole
250 mg
$ 45.00

Biosynth Carbosynth
(-)-Benzotetramisole
500 mg
$ 78.00

Total 16 raw suppliers

Chemical Property of (-)-Benzotetramisole

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:93.0 to 97.0 °C
Boiling Point:428.075°C at 760 mmHg
PKA:7.53±0.40(Predicted)
Flash Point:212.692°C
PSA：45.53000
Density:1.328g/cm³
LogP:2.79400
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:soluble in Methanol
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:252.07211956
Heavy Atom Count:18
Complexity:348

Purity/Quality:

97% ^*data from raw suppliers

(-)-Benzotetramisole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(N=C2N1C3=CC=CC=C3S2)C4=CC=CC=C4
Isomeric SMILES:C1[C@@H](N=C2N1C3=CC=CC=C3S2)C4=CC=CC=C4

Technology Process of (-)-Benzotetramisole

There total 4 articles about (-)-Benzotetramisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1235891-51-6
(S)-N-(2-benzothiazolyl)-2-hydroxy-1-phenylethylamine

: 950194-37-3,885051-07-0
(S)-(-)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole

Guidance literature:: (S)-N-(2-benzothiazolyl)-2-hydroxy-1-phenylethylamine; With methanesulfonyl chloride; triethylamine; In dichloromethane; at 0 ℃; for 2h; Inert atmosphere;

With methanol; In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;

With triethylamine; In dichloromethane; at 55 ℃; for 12h; Inert atmosphere;
DOI:10.1021/jo1020344

Reference yield: 71.0%

: (S)-2-isocyano-2-phenylethyl 4-methylbenzenesulfonate

: tert-butyl (2-((2-aminophenyl)disulfanyl)phenyl)carbamate

: 950194-37-3,885051-07-0
(S)-(-)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole

Guidance literature:: tert-butyl (2-((2-aminophenyl)disulfanyl)phenyl)carbamate; With N-chloro-succinimide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; In 1,2-dichloro-ethane; at 20 ℃; for 2h; Inert atmosphere;

(S)-2-isocyano-2-phenylethyl 4-methylbenzenesulfonate; In 1,2-dichloro-ethane; for 2h; Inert atmosphere;
DOI:10.1021/acs.orglett.9b00275

Reference yield:

: 1141-88-4
2-Aminophenyl disulfide

: 950194-37-3,885051-07-0
(S)-(-)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: TEA / methanol / 100 °C

2.1: N-chloro-succinimide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / 1,2-dichloro-ethane / 2 h / 20 °C / Inert atmosphere

2.2: 2 h / Inert atmosphere

With N-chloro-succinimide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; In methanol; 1,2-dichloro-ethane;
DOI:10.1021/acs.orglett.9b00275