9-Amino(9-deoxy)epi-cinchonidine trihydrochloride

Base Information

Chemical Name:9-Amino(9-deoxy)epi-cinchonidine trihydrochloride
CAS No.:850409-61-9
Molecular Formula:C19H23N3
Molecular Weight:293.412
Hs Code.:
Mol file:850409-61-9.mol

Synonyms:9-amino(9-deoxy)epicinchonidine;(S)-quinolin-4-yl((2S)-8-vinylquinuclidin-2-yl)methanamine;9-amino-(9-deoxy)epicinchonidine;

Suppliers and Price of 9-Amino(9-deoxy)epi-cinchonidine trihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 12 raw suppliers

Chemical Property of 9-Amino(9-deoxy)epi-cinchonidine trihydrochloride

Chemical Property:

PSA：42.15000
LogP:3.76920

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 9-Amino(9-deoxy)epi-cinchonidine trihydrochloride

There total 4 articles about 9-Amino(9-deoxy)epi-cinchonidine trihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: (8S,9S)-9-azido-9-epicinchonidine

: 850409-61-9
(S)-quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanamine

Guidance literature:: With triphenylphosphine; In tetrahydrofuran; at 50 ℃; for 4h;

Reference yield: 84.0%

: 118-10-5,485-70-1,485-71-2,550-54-9,40134-63-2,72402-55-2,72402-56-3
(1S,3R,4S,8S,9S)-9-hydroxy-cinchonane

: 850409-61-9
(S)-quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanamine

Guidance literature:: (1S,3R,4S,8S,9S)-9-hydroxy-cinchonane; With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 ℃; for 0.25h;

With diphenyl phosphoryl azide; at 45 ℃; for 28h;
DOI:10.1002/anie.201811471

Reference yield: 56.0%

: 485-71-2
Cinchonidin

: 850409-61-9
(S)-quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanamine

Guidance literature:: Cinchonidin; With di-isopropyl azodicarboxylate; diphenyl phosphoryl azide; triphenylphosphine; In tetrahydrofuran; at 0 - 50 ℃; for 14h;

With water; In tetrahydrofuran; at 20 ℃; for 3h;