5-Bromoisoquinolin-3-amine

Base Information

Chemical Name:5-Bromoisoquinolin-3-amine
CAS No.:1192815-01-2
Molecular Formula:C9H7BrN2
Molecular Weight:223.07
Hs Code.:2933499090
DSSTox Substance ID:DTXSID30697427
Wikidata:Q82627323
Mol file:1192815-01-2.mol

Synonyms:5-BROMOISOQUINOLIN-3-AMINE;1192815-01-2;3-Isoquinolinamine, 5-bromo-;5-Bromo-3-Isoquinolinamine;SCHEMBL559239;DTXSID30697427;VZWSVFLRMXYQLA-UHFFFAOYSA-N;MFCD15526591;AS-38812;CS-0100035;EN300-3005946;A928012

Suppliers and Price of 5-Bromoisoquinolin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromoisoquinolin-3-amine
50mg
$ 220.00

SynQuest Laboratories
3-Amino-5-bromoisoquinoline
1 g
$ 900.00

SynQuest Laboratories
3-Amino-5-bromoisoquinoline
250 mg
$ 360.00

SynQuest Laboratories
3-Amino-5-bromoisoquinoline
500 mg
$ 608.00

Matrix Scientific
5-Bromoisoquinolin-3-amine
5g
$ 2664.00

Matrix Scientific
5-Bromoisoquinolin-3-amine
500mg
$ 596.00

Matrix Scientific
5-Bromoisoquinolin-3-amine
1g
$ 888.00

Crysdot
5-Bromoisoquinolin-3-amine 95+%
1g
$ 1072.00

Chemenu
5-bromoisoquinolin-3-amine 95%
1g
$ 1010.00

Apolloscientific
3-Amino-5-bromoisoquinoline
1g
$ 759.00

Total 12 raw suppliers

Chemical Property of 5-Bromoisoquinolin-3-amine

Chemical Property:

Boiling Point:387.6±22.0 °C(Predicted)
PKA:4.07±0.43(Predicted)
PSA：39.64000
Density:1.649±0.06 g/cm3(Predicted)
LogP:2.50960
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:221.97926
Heavy Atom Count:12
Complexity:163

Purity/Quality:

97% ^*data from raw suppliers

5-Bromoisoquinolin-3-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=CN=C(C=C2C(=C1)Br)N

Technology Process of 5-Bromoisoquinolin-3-amine

There total 4 articles about 5-Bromoisoquinolin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1192815-00-1
N-(3-bromo-benzyl)-2,2-diethoxy-acetamidine

: 1192815-02-3
7-bromoisoquinolin-3-amine

: 1192815-01-2
5-bromo-isoquinolin-3-ylamine

Guidance literature:: With sulfuric acid; at 40 ℃; for 54h; Overall yield = 57 %; Overall yield = 1 g;

Reference yield:

: 39959-54-1
3-bromobenzylamine hydrochloride

: 1192815-01-2
5-bromo-isoquinolin-3-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 2 h / 70 °C / Inert atmosphere

2: sulfuric acid / 22 h / 0 - 20 °C

With sulfuric acid; In methanol;
DOI:10.1021/acs.jmedchem.6b01834