2-AMino-3-benzoyl-5-Methylthiophene

Base Information

• Chemical Name: 2-AMino-3-benzoyl-5-Methylthiophene
• CAS No.: 30163-51-0
• Molecular Formula: C12H11NOS
• Molecular Weight: 217.291
• Mol file: 30163-51-0.mol

Synonyms:2-Amino-3-benzoyl-5-methylthiophen;(2-Amino-5-methyl-thiophen-3-yl)-phenyl-methanone;

Chemical Property of 2-AMino-3-benzoyl-5-Methylthiophene

Chemical Property:

• Melting Point: 123 - 126 °C
• PSA: 71.33000
• LogP: 3.45090

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
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Technology Process of 2-AMino-3-benzoyl-5-Methylthiophene

There total 1 articles about 2-AMino-3-benzoyl-5-Methylthiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (2-amino-5-methyl-thiophen-3-yl)-phenyl-methanone (30163-51-0)

Guidance literature:

Phenacylcyanid, Dimethylformamid, Schwefel, Triethylamin, Propionaldehyd;

DOI:10.1007/BF00910583

Reference yield: 55.0%

(2-amino-5-methyl-thiophen-3-yl)-phenyl-methanone (30163-51-0) + 2-(benzotriazol-1-yl)-N-(benzyloxycarbonyl)glycine (124676-19-3) → C28H23N5O4S

Guidance literature:

2-(benzotriazol-1-yl)-N-(benzyloxycarbonyl)glycine; With oxalyl dichloride; In tetrahydrofuran; N,N-dimethyl-formamide; for 0.5h; Cooling with ice;

(2-amino-5-methyl-thiophen-3-yl)-phenyl-methanone; With 4-pyrrolidin-1-ylpyridine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 1h;

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