2-Chloro-4-nitrophenyl-a-D-mannopyranoside

Base Information

• Chemical Name: 2-Chloro-4-nitrophenyl-a-D-mannopyranoside
• CAS No.: 65446-24-4
• Molecular Formula: C12H14ClNO8
• Molecular Weight: 335.698

Synonyms:2-Chloro-4-nitrophenyl-a-D-mannopyranoside;2-Chloro-4-nitrophenyl-α-D-Mannopyranoside;(2R,3S,4S,5S,6R)-2-(2-Chloro-4-nitrophenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Chemical Property of 2-Chloro-4-nitrophenyl-a-D-mannopyranoside

Chemical Property:

• Boiling Point: 591.2±50.0 °C(Predicted)
• PKA: 12.57±0.70(Predicted)
• PSA: 145.20000
• Density: 1.675±0.06 g/cm3 (20 oC 760 Torr), Calc.*
• LogP: -0.04990

Purity/Quality:

99%, ^*data from raw suppliers

2-Chloro-4-nitrophenyl a-D-mannopyranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Chloro-4-nitrophenyl-a-D-mannopyranoside

There total 2 articles about 2-Chloro-4-nitrophenyl-a-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2-chloro-4-nitrophenyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside (153823-58-6) → 2-chloro-4-nitrophenyl α-D-mannopyranoside (65446-24-4,119047-14-2)

Guidance literature:

With ammonia; In methanol; at 20 ℃;

DOI:10.1016/j.jcat.2015.12.026

Reference yield:

2-chloro-4-nitrophenol (619-08-9) + per-O-acetyl-α-D-mannopyranose (4163-65-9) → 2-chloro-4-nitrophenyl α-D-mannopyranoside (65446-24-4,119047-14-2)

Guidance literature:

Multi-step reaction with 2 steps

1: boron trifluoride diethyl etherate / dichloromethane / 96 h / Reflux; Inert atmosphere

2: ammonia / methanol / 20 °C

With boron trifluoride diethyl etherate; ammonia; In methanol; dichloromethane;

DOI:10.1016/j.jcat.2015.12.026

Reference yield:

2-chloro-4-nitrophenyl α-D-mannopyranoside (65446-24-4,119047-14-2) → 4-amino-2-chlorophenyl α-D-mannopyranoside (1403988-92-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 1h; under 750.075 Torr;

DOI:10.1039/b610745a

upstream raw materials:

2-chloro-4-nitrophenyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside

2-chloro-4-nitrophenol

per-O-acetyl-α-D-mannopyranose

Downstream raw materials:

4-amino-2-chlorophenyl α-D-mannopyranoside

2-chloro-4-[(2-(4-methylpiperazin-1-yl)-3,4-dioxocyclobuten-1-yl)amino]phenyl α-D-mannopyranoside

o-chloro-p-[N-(2-ethoxy-3,4-dioxocyclobut-1-enyl)amino]phenyl α-D-mannopyranoside

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 65446-24-4 2-Chloro-4-nitrophenyl-a-D-mannopyranoside

Send

Send

Metric Ton KG G Pound L ML

Send

Send