3-Methyl-9-phenyl-9H-carbazole

Base Information

• Chemical Name: 3-Methyl-9-phenyl-9H-carbazole
• CAS No.: 1202362-88-6
• Molecular Formula: C19H15N
• Molecular Weight: 257.335
• Hs Code.: 2933990090
• Mol file: 1202362-88-6.mol

Synonyms:3-Methyl-9-phenyl-9h-carbazole;QC-1248;

Chemical Property of 3-Methyl-9-phenyl-9H-carbazole

Chemical Property:

• Melting Point: 205.4-207.0℃
• PSA: 4.93000
• LogP: 5.09210
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

3-Methyl-9-phenyl-9H-carbazole 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Methyl-9-phenyl-9H-carbazole

There total 16 articles about 3-Methyl-9-phenyl-9H-carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2′-chloro-5-methyl-N-phenyl-[1,1′-biphenyl]-2-amine → 3-methyl-9-phenyl-9H-carbazole (1202362-88-6)

Guidance literature:

With potassium tert-butylate; In diethyl ether; dimethyl sulfoxide; at 40 ℃; for 3h; Schlenk technique; Inert atmosphere; Irradiation;

DOI:10.1021/jo5024393

Reference yield: 75.0%

2-iodo-5-methyl-1,1'-biphenyl (1214389-60-2) + aniline (62-53-3) → 3-methyl-9-phenyl-9H-carbazole (1202362-88-6)

Guidance literature:

With copper diacetate; palladium diacetate; caesium carbonate; triphenylphosphine; In N,N-dimethyl-formamide; at 120 ℃; for 12h; Sealed tube;

DOI:10.1039/c9cc09493h

Reference yield: 71.0%

3-Methyl-9H-carbazole (4630-20-0) + iodobenzene (591-50-4) → 3-methyl-9-phenyl-9H-carbazole (1202362-88-6)

Guidance literature:

With tris[2-phenylpyridinato-C₂,N]iridium(III); copper(l) iodide; lithium tert-butoxide; In dimethyl sulfoxide; at 32 ℃; for 18h; Inert atmosphere; Irradiation;

DOI:10.1021/acs.orglett.5b01645

upstream raw materials:

1-methyl-4-nitrosobenzene

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

4-tolyl iodide

diphenylamine

Downstream raw materials:

3-bromo-6-methyl-9-phenyl-9H-carbazole

Refernces

• 1、 Huang, Huawen,Deng, Kun,Deng, Guo-Jun. "Redox-neutral decarboxylative photocyclization of anthranilic acids". supporting information. p. 8243 - 8247. Retrieved 2020/12/29.
• 2、 He, Zhi-Tao,Li, Haoquan,Haydl, Alexander M.,Whiteker, Gregory T.,Hartwig, John F.. "Trimethylphosphate as a Methylating Agent for Cross Coupling: A Slow-Release Mechanism for the Methylation of Arylboronic Esters". supporting information. p. 17197 - 17202. Retrieved 2018/12/14.