N^2^-[(2R)-2-{(1S)-1-[Formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl]-N,3-dimethyl-L-valinamide

Base Information

Chemical Name:N^2^-[(2R)-2-{(1S)-1-[Formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl]-N,3-dimethyl-L-valinamide
CAS No.:260264-93-5
Molecular Formula:C21H33N3O4
Molecular Weight:391.511
Hs Code.:
ChEMBL ID:CHEMBL1229516
DSSTox Substance ID:DTXSID20433275
Nikkaji Number:J2.224.878B
Pharos Ligand ID:DQ5BF6VS84WR
Wikidata:Q27449782
Mol file:260264-93-5.mol

$N^2^-[(2R)-2-{(1S)-1-[Formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl]-N,3-dimethyl-L-valinamide$

Synonyms:3-(formylhydroxyamino)-2-(3-phenyl-1-propyl)butanoic acid (2,2-dimethyl-1-methylcarbamoyl-1-propyl)amide;GI 254023;GI-254023;GI254023;GI254023X

Suppliers and Price of N^2^-[(2R)-2-{(1S)-1-[Formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl]-N,3-dimethyl-L-valinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
GI 254023X
1mg
$ 340.00

TRC
GI254023X
250mg
$ 4960.00

Tocris
GI254023X ≥98%(HPLC)
1
$ 184.00

Sigma-Aldrich
GI254023X ≥98% (HPLC)
25mg
$ 710.00

Sigma-Aldrich
GI254023X ≥98% (HPLC)
5mg
$ 178.00

DC Chemicals
GI254023X >98%
250 mg
$ 1450.00

CSNpharm
GI254023X
1mg
$ 115.00

CSNpharm
GI254023X
5mg
$ 189.00

Crysdot
GI254023X(GI4023;SRI028594) 95+%
5mg
$ 196.00

ChemScene
GI254023X 99.84%
1mg
$ 144.00

Total 16 raw suppliers

Chemical Property of N^2^-[(2R)-2-{(1S)-1-[Formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl]-N,3-dimethyl-L-valinamide

Chemical Property:

PKA:8.48±0.69(Predicted)
PSA：105.72000
Density:1.112±0.06 g/cm3(Predicted)
LogP:4.45500
Storage Temp.:2-8°C
Solubility.:DMSO: soluble15mg/mL, clear
XLogP3:2.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:391.24710654
Heavy Atom Count:28
Complexity:512

Purity/Quality:

99%, ^*data from raw suppliers

GI 254023X ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(CCCC1=CC=CC=C1)C(=O)NC(C(=O)NC)C(C)(C)C)N(C=O)O
Isomeric SMILES:C[C@@H]([C@@H](CCCC1=CC=CC=C1)C(=O)N[C@H](C(=O)NC)C(C)(C)C)N(C=O)O
Uses GI 254023X is an ADAM10 metaloproteinase inhibitor. GI254023X has been used to inhibit ADAM10 (ADAM metallopeptidase domain 10).

Technology Process of N^2^-[(2R)-2-{(1S)-1-[Formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl]-N,3-dimethyl-L-valinamide

There total 2 articles about N^2^-[(2R)-2-{(1S)-1-[Formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl]-N,3-dimethyl-L-valinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%