6-Acetamido-1-oxo-2,3-dihydro-1H-indene-4-carboxylic acid

Base Information

Chemical Name:6-Acetamido-1-oxo-2,3-dihydro-1H-indene-4-carboxylic acid
CAS No.:224181-99-1
Molecular Formula:C12H11NO4
Molecular Weight:233.22004
Hs Code.:2924299090
Mol file:224181-99-1.mol

Synonyms:6-acetylamino-1-oxo-indan-4-carboxylic acid;6-Acetamido-1-oxo-2,3-dihydro-1H-indene-4-carboxylic acid;6-(acetylamino)-1-oxoindane-4-carboxylic acid;

Suppliers and Price of 6-Acetamido-1-oxo-2,3-dihydro-1H-indene-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-ACETAMIDO-1-OXO-2,3-DIHYDRO-1H-INDENE-4-CARBOXYLIC ACID 95.00%
5MG
$ 500.60

Total 3 raw suppliers

Chemical Property of 6-Acetamido-1-oxo-2,3-dihydro-1H-indene-4-carboxylic acid

Chemical Property:

PSA：86.96000
LogP:2.12160

Purity/Quality:

97% ^*data from raw suppliers

6-ACETAMIDO-1-OXO-2,3-DIHYDRO-1H-INDENE-4-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-Acetamido-1-oxo-2,3-dihydro-1H-indene-4-carboxylic acid

There total 3 articles about 6-Acetamido-1-oxo-2,3-dihydro-1H-indene-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 224181-98-0
5-acetylamino-2-(2-carboxy-ethyl)-benzoic acid

: 224181-99-1
6-acetylamino-1-oxo-indan-4-carboxylic acid

Guidance literature:: With aluminium trichloride; sodium chloride; at 140 ℃; for 2h;
DOI:10.1016/S0040-4020(99)00097-6

Reference yield:

: 90945-77-0
5-nitro-2-(2-carboxy-ethyl)-benzoic acid

: 224181-99-1
6-acetylamino-1-oxo-indan-4-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: H₂, aq. NaOH / Pd/C / 18 h

2: Et₃N / diethyl ether / 1) 0 deg C, 1 h; 2) rt, 30 min

3: 77 percent / AlCl₃, NaCl / 2 h / 140 °C

With sodium hydroxide; aluminium trichloride; hydrogen; triethylamine; sodium chloride; palladium on activated charcoal; In diethyl ether;
DOI:10.1016/S0040-4020(99)00097-6

Reference yield:

: 94237-93-1
5-Amino-2-(2-carboxyethyl)-benzoesaeure

: 224181-99-1
6-acetylamino-1-oxo-indan-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / diethyl ether / 1) 0 deg C, 1 h; 2) rt, 30 min

2: 77 percent / AlCl₃, NaCl / 2 h / 140 °C

With aluminium trichloride; triethylamine; sodium chloride; In diethyl ether;
DOI:10.1016/S0040-4020(99)00097-6