tert-Butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate

Base Information

Chemical Name:tert-Butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate
CAS No.:1147557-68-3
Molecular Formula:C12H21NO4
Molecular Weight:243.303
Hs Code.:
Mol file:1147557-68-3.mol

Synonyms:7-Boc-3-oxa-7-azabicyclo[3.3.1]nonan-9-ol;tert-Butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carbo...;tert-Butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate;tert-Butyl (1R,5S)-9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate;Tert-Butyl 9-Hydroxy-3-Oxa-7-Azabicyclo[3.3.1]Nonane-7-Carboxylate(WX125246);9-HYDROXY-3-OXA-7-AZABICYCLO[ 3.3.1]NONANE-7- CARBOXYLIC ACID TERT-BUTYLESTER;3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-hydroxy-, 1,1-dimethylethyl ester

Suppliers and Price of tert-Butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-Butyl9-Hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate
100mg
$ 285.00

Chemenu
tert-butyl9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate 95%
1g
$ 916.00

Total 7 raw suppliers

Chemical Property of tert-Butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate

Chemical Property:

PSA：59.00000
LogP:0.79850

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl9-Hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-Butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate

There total 5 articles about tert-Butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.8%

: 24424-99-5
di-tert-butyl dicarbonate

: 934182-73-7
7-benzyl-3-oxa-7-azabicyclo[3.3.1]nonan-9-ol

: 1147557-68-3
tert-butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate

Guidance literature:: 7-benzyl-3-oxa-7-azabicyclo[3.3.1]nonan-9-ol; With hydrogen; palladium 10% on activated carbon; at 20 ℃; under 760.051 Torr;

di-tert-butyl dicarbonate; With triethylamine; at 20 ℃;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1246187-79-0
3-oxa-7-azabicyclo[3.3.1]nonan-9-ol

: 1147557-68-3
tert-butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate

Guidance literature:: In tetrahydrofuran; water; at 0 - 20 ℃; for 15h;

Reference yield:

: 29943-42-8,143562-54-3
Tetrahydro-4H-pyran-4-one

: 1147557-68-3
tert-butyl 9-hydroxy-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid / methanol / 2.25 h / 65 °C

1.3: 0.5 h

2.1: sodium tetrahydroborate / ethanol; tetrahydrofuran / 4 h / 20 °C / Cooling with ice

3.1: hydrogen / palladium(II) hydroxide / ethanol / 2.5 h / 2585.81 Torr

4.1: water; tetrahydrofuran / 15 h / 0 - 20 °C

With sodium tetrahydroborate; hydrogen; acetic acid; palladium(II) hydroxide; In tetrahydrofuran; methanol; ethanol; water;