(1S)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)MethanaMine dihydrochloride

Base Information

Chemical Name:(1S)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)MethanaMine dihydrochloride
CAS No.:18797-90-5
Molecular Formula:C20H27Cl2N3O
Molecular Weight:396.35388
Hs Code.:
Mol file:18797-90-5.mol

Synonyms:(1S)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)MethanaMine dihydrochloride

Suppliers and Price of (1S)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)MethanaMine dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 6 raw suppliers

Chemical Property of (1S)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)MethanaMine dihydrochloride

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (1S)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)MethanaMine dihydrochloride

There total 11 articles about (1S)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)MethanaMine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 130-95-0
Quinine

: 1231763-32-8,18797-90-5
(S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanamine hydrochloride

Guidance literature:: Quinine; With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

With diphenyl phosphoryl azide; In tetrahydrofuran; at 50 ℃; for 8h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; Inert atmosphere;
DOI:10.1039/d1ob01306h

Reference yield: 84.0%

: 56-54-2,130-95-0,572-59-8,572-60-1,42151-59-7,47342-58-5,72402-50-7,72402-51-8,72402-52-9,72402-53-0,101143-86-6,101143-87-7,101143-88-8,146925-10-2
qunidine

: 1231763-32-8,18797-90-5
(S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanamine hydrochloride

Guidance literature:: qunidine; With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 ℃; for 0.166667h; Inert atmosphere;

With diphenyl phosphoryl azide; In tetrahydrofuran; at 20 - 45 ℃; for 8h; Inert atmosphere;

With hydrogenchloride; In dichloromethane; Inert atmosphere;
DOI:10.1021/jo401352z

Reference yield: 82.0%

: 130-95-0
quinine

: 1231763-32-8,18797-90-5
C₂₀H₂₅N₃O*3ClH

Guidance literature:: quinine; With di-isopropyl azodicarboxylate; diphenylphosphoranyl azide; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 16h; Inert atmosphere;

With triphenylphosphine; In water; at 20 - 50 ℃; for 4h;

With hydrogenchloride; In dichloromethane; water;
DOI:10.1039/c8cc00609a