(2S)-diMethyl 8-acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole-1,2(2H)-dicarboxylate

Base Information

Chemical Name:(2S)-diMethyl 8-acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole-1,2(2H)-dicarboxylate
CAS No.:79465-85-3
Molecular Formula:C16H18N2O5
Molecular Weight:318.329
Hs Code.:
Mol file:79465-85-3.mol

Synonyms:(S)-dimethyl 2-aminohexanedioate hydrochloride;Dimethyl (2R,6S)-piperidine-2,6-dicarboxylate hydrochloride;dimethyl (2S,3aR,8aS)-8-acetyl-1,2,3,3a,8,8a-hexahydropyrrolo<2,3-b>indole-1,2-dicarboxylate;dimethyl (2S)-2-aminoadipate;dimethyl meso-(2R,6S)-piperidine-2,6-dicarboxylate hydrochloride;1,2-Dimethoxycarbonyl-8-acetyl-1,2,3,3a,8,8a-hexahydropyrrolo<2,3-b>indole;dimethyl (S)-2-aminohexanedioate;

Suppliers and Price of (2S)-diMethyl 8-acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole-1,2(2H)-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
(2S)-dimethyl8-acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole-1,2(2H)-dicarboxylate
500mg
$ 1980.00

Total 6 raw suppliers

Chemical Property of (2S)-diMethyl 8-acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole-1,2(2H)-dicarboxylate

Chemical Property:

PSA：76.15000
LogP:1.47940

Purity/Quality:

NLT 98% ^*data from raw suppliers

(2S)-dimethyl8-acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole-1,2(2H)-dicarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S)-diMethyl 8-acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole-1,2(2H)-dicarboxylate

There total 8 articles about (2S)-diMethyl 8-acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole-1,2(2H)-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 108-24-7
acetic anhydride

: 79465-82-0
L-(2β,3aα,8aα)-1,2,3,3a,8,8a-hexahydro-1,2-dimethoxycarbonylpyrrolo<2,3-b>indole

: 79465-85-3
L-(2β,3aα,8aα)-8-acetyl-1,2-dimethoxycarbonyl-1,2,3,3a,8,8a-hexahydropyrrolo<2,3-b>indole

Guidance literature:: With pyridine; at 20 ℃; for 20h;
DOI:10.1016/j.tetlet.2007.12.130

Reference yield:

: 66377-68-2
N_b-methoxycarbonyl-DL-tryptophan methyl ester

: 67811-39-6,79465-83-1,79465-84-2,79465-85-3,79465-86-4
DL-(2β,3aα,8aα)-8-acetyl-1,2-dimethoxycarbonyl-1,2,3,3a,8,8a-hexahydropyrrolo<2,3-b>indole

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / 85percent phosphoric acid / 3 h / Ambient temperature

2: pyridine

With phosphoric acid; In pyridine;
DOI:10.1016/S0040-4020(01)92088-5