2-(5-fluoropentyl)-2-methylmalonic acid

Base Information

Chemical Name:2-(5-fluoropentyl)-2-methylmalonic acid
CAS No.:1216897-16-3
Molecular Formula:C9H15FO4
Molecular Weight:206.21
Hs Code.:
Mol file:1216897-16-3.mol

Synonyms:5-fluoropentyl-2-methyl-malonic acid;(5-fluoropentyl)(methyl)propanedioic acid;UNII-W50XI028PF;ML-10;2-(5-fluoropentyl)-2-methylmalonic acid;

Suppliers and Price of 2-(5-fluoropentyl)-2-methylmalonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
ML-10
500mg
$ 1980.00

Total 7 raw suppliers

Chemical Property of 2-(5-fluoropentyl)-2-methylmalonic acid

Chemical Property:

PSA：74.60000
LogP:1.69180

Purity/Quality:

≥95% ^*data from raw suppliers

ML-10 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(5-fluoropentyl)-2-methylmalonic acid

There total 11 articles about 2-(5-fluoropentyl)-2-methylmalonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1415564-81-6
di-tert-butyl 2-(5-fluoropentyl)-2-methylmalonate

: 1216897-16-3
2-(5-fluoropentyl)-2-methylmalonic acid

Guidance literature:: With water; trifluoroacetic acid; at 20 ℃; for 24h;
DOI:10.1016/j.bmc.2013.11.019

Reference yield: 86.0%

: diethyl 2-(5-fluoropentyl)-2-methylmalonate

: 1216897-16-3
2-(5-fluoropentyl)-2-methylmalonic acid

Guidance literature:: With lithium hydroxide monohydrate; In tetrahydrofuran; methanol; water; at 20 ℃; for 24h;
DOI:10.1002/jlcr.3016

Reference yield:

: 174583-20-1
diethyl 2-(5-bromopentyl)-2-methylmalonate

: 1216897-16-3
2-(5-fluoropentyl)-2-methylmalonic acid

Guidance literature:: Multi-step reaction with 3 steps

1: acetonitrile / 24 h / Reflux; Inert atmosphere

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 60 °C / Inert atmosphere

3: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 24 h / 20 °C

With lithium hydroxide monohydrate; tetrabutyl ammonium fluoride; In tetrahydrofuran; methanol; water; acetonitrile;
DOI:10.1002/jlcr.3016