(E)-1-benzyl-4-((5,6-dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridinium chloride

Base Information

• Chemical Name: (E)-1-benzyl-4-((5,6-dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridinium chloride
• CAS No.: 1188913-39-4
• Molecular Formula: C24H22ClNO3
• Molecular Weight: 407.88938
• Mol file: 1188913-39-4.mol

Synonyms:(E)-1-benzyl-4-((5,6-diMethoxy-1-oxo-1H-inden-2(3H)-ylidene)Methyl)pyridiniuM chloride;(E)-1-benzyl-4-((5,6-dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridin-1-ium chloride;1-Benzyl-4-((5,6-dimethoxy-1-oxo-1,3-dihydro-2H-inden-2-ylidene)methyl)pyridin-1-ium chloride

Chemical Property of (E)-1-benzyl-4-((5,6-dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridinium chloride

Chemical Property:

• PSA: 39.41000
• LogP: 0.86600

Purity/Quality:

NLT 98% ^*data from raw suppliers

(E)-1-Benzyl-4-((5,6-dimethoxy-1-oxo-1h-inden-2(3h)-ylidene)methyl)pyridiniumChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (E)-1-Benzyl-4-((5,6-dimethoxy-1-oxo-1h-inden-2(3h)-ylidene)methyl)pyridinium Chloride is used as a reactant in the preparation of Donepezil Hydrochloride (D531750), a nootropic.

Technology Process of (E)-1-benzyl-4-((5,6-dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridinium chloride

There total 3 articles about (E)-1-benzyl-4-((5,6-dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridinium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

5,6-dimethoxy-2-[(pyridin-4-yl)methylene]-1-indanone (4803-74-1) + benzyl chloride (100-44-7) → 1-benzyl-4-[(5,6-dimethoxy-1-indanone-2-ylidene)methyl]pyridinium chloride (1188913-39-4)

Guidance literature:

In acetonitrile; at 80 ℃; for 48h; Temperature; Time;

DOI:10.1007/s13738-019-01804-1

Reference yield:

pyridine-4-carbaldehyde (872-85-5) → 1-benzyl-4-[(5,6-dimethoxy-1-indanone-2-ylidene)methyl]pyridinium chloride (1188913-39-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol; water / 20 °C / Inert atmosphere

2: acetonitrile / 48 h / 80 °C

With sodium hydroxide; In ethanol; water; acetonitrile; 1: |Aldol Condensation;

DOI:10.1007/s13738-019-01804-1

Reference yield:

5,6-dimethoxy-1-indanone (2107-69-9) → 1-benzyl-4-[(5,6-dimethoxy-1-indanone-2-ylidene)methyl]pyridinium chloride (1188913-39-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol; water / 20 °C / Inert atmosphere

2: acetonitrile / 48 h / 80 °C

With sodium hydroxide; In ethanol; water; acetonitrile; 1: |Aldol Condensation;

DOI:10.1007/s13738-019-01804-1

upstream raw materials:

pyridine-4-carbaldehyde

5,6-dimethoxy-1-indanone

5,6-dimethoxy-2-[(pyridin-4-yl)methylene]-1-indanone

benzyl chloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1188913-39-4 (E)-1-benzyl-4-((5,6-dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridinium chloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send