tert-butyl (3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate coMpound with tert-butyl (3aS,4S,6aR)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate (1:1)

Base Information

Chemical Name:tert-butyl (3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate coMpound with tert-butyl (3aS,4S,6aR)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate (1:1)
CAS No.:874949-35-6
Molecular Formula:C₁₂H₂₂N₂O₂
Molecular Weight:226.319
Hs Code.:
Mol file:874949-35-6.mol

tert-butyl (3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate coMpound with tert-butyl (3aS,4S,6aR)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate (1:1)

Synonyms:TERT-BUTYL ((3AR,4R,6AS)-OCTAHYDROCYCLOPENTA[C]PYRROL-4-YL)CARBAMATE;tert-butyl (3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate coMpound with tert-butyl (3aS,4S,6aR)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate (1:1)

Suppliers and Price of tert-butyl (3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate coMpound with tert-butyl (3aS,4S,6aR)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate (1:1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl((3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-yl)carbamate 97%
1g
$ 1768.00

Total 3 raw suppliers

Chemical Property of tert-butyl (3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate coMpound with tert-butyl (3aS,4S,6aR)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate (1:1)

Chemical Property:

PSA：107.70000
LogP:4.08460

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl((3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-yl)carbamate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl (3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate coMpound with tert-butyl (3aS,4S,6aR)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate (1:1)

There total 8 articles about tert-butyl (3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate coMpound with tert-butyl (3aS,4S,6aR)-octahydrocyclopenta[c]pyrrol-4-ylcarbaMate (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1,1-dimethylethyl (+/-)-[(3aR,4R,6aS)-2-(phenylmethyl)octahydrocyclopenta[c]pyrrol-4-yl]carbamate

: 874949-35-6
1,1-dimethylethyl (+/-)-(3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbamate

Guidance literature:: With hydrogen; palladium dihydroxide; In ethanol; for 5h; under 2585.81 Torr; Parr shaker;

Reference yield:

: 1228030-06-5
tert-butyl (3aR,4S,6aS)-2-benzyloctahydrocyclopenta[c]pyrrol-4-ylcarbamate

: 1228030-08-7,874949-35-6
tert-butyl (3aR,4S,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbamate

Guidance literature:: With 20% palladium hydroxide-activated charcoal; hydrogen; In ethanol; at 20 ℃; for 4h; under 1551.49 Torr;
DOI:10.1016/j.bmcl.2013.06.074

Reference yield:

: (3aR,6aS)-2-benzyl-tetrahydrocyclopenta[c]pyrrol-4(1H,2H,5H)-one

: 1228030-08-7,874949-35-6
tert-butyl (3aR,4S,6aS)-octahydrocyclopenta[c]pyrrol-4-ylcarbamate

Guidance literature:: Multi-step reaction with 6 steps

1: sodium tetrahydroborate / methanol / 16 h / -78 - 20 °C

2: triethylamine / dichloromethane / 0.5 h / 25 °C

3: sodium azide / N,N-dimethyl acetamide / 16 h / 90 °C

4: triphenylphosphine; water / tetrahydrofuran / 1 h / 80 °C

5: triethylamine / dichloromethane

6: 20% palladium hydroxide-activated charcoal; hydrogen / ethanol / 4 h / 20 °C / 1551.49 Torr

With sodium tetrahydroborate; sodium azide; 20% palladium hydroxide-activated charcoal; water; hydrogen; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl acetamide; 4: |Staudinger Azide Reduction;
DOI:10.1016/j.bmcl.2013.06.074