(2R,3S)-Rel-2,3-bis(4-chlorophenyl)-2,3-butanediaMine

Base Information

• Chemical Name: (2R,3S)-Rel-2,3-bis(4-chlorophenyl)-2,3-butanediaMine
• CAS No.: 939983-16-1
• Molecular Formula: C16H18Cl2N2
• Molecular Weight: 309.238
• Mol file: 939983-16-1.mol

Synonyms:meso-2,3-bis-(4-chlorophenyl)-2,3-butanediamine;4,4'-((2R,3S)-Butane-2,3-diyl)bis(chlorobenzene);meso-bis(4-chlorophenyl)-ethane-1,2-diamine;

Chemical Property of (2R,3S)-Rel-2,3-bis(4-chlorophenyl)-2,3-butanediaMine

Chemical Property:

• PSA: 0.00000
• LogP: 5.90060

Purity/Quality:

97% ^*data from raw suppliers

4,4'-((2R,3S)-Butane-2,3-diyl)bis(chlorobenzene) 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2R,3S)-Rel-2,3-bis(4-chlorophenyl)-2,3-butanediaMine

There total 1 articles about (2R,3S)-Rel-2,3-bis(4-chlorophenyl)-2,3-butanediaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

para-chloroacetophenone (99-91-2) → meso-2,3-bis-(4-chlorophenyl)-2,3-butanediamine (939983-16-1)

Guidance literature:

para-chloroacetophenone; With lithium aluminium tetrahydride; titanium(III) chloride; ammonia; In tetrahydrofuran; at -15 - 20 ℃; Heating / reflux;

With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃; Acidic aqueous solution;

With sodium hydroxide; In water; Alkaline aqueous solution;

Reference yield: 100.0%

meso-2,3-bis-(4-chlorophenyl)-2,3-butanediamine (939983-16-1) + sodium 6-tert-butyl-4-ethoxynicotinate (1415334-30-3) → rac-N-[(1R,2S)-2-amino-1,2-bis(4-chlorophenyl)-1-methylpropyl]-6-tert-butyl-4-ethoxynicotinamide

Guidance literature:

meso-2,3-bis-(4-chlorophenyl)-2,3-butanediamine; sodium 6-tert-butyl-4-ethoxynicotinate; With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In 2-methyltetrahydrofuran; for 0.166667h; Large scale;

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 2-methyltetrahydrofuran; Large scale;

DOI:10.1021/op300294g

Reference yield: 85.0%

meso-2,3-bis-(4-chlorophenyl)-2,3-butanediamine (939983-16-1) + 6-tert-butyl-4-ethoxy-nicotinoyl chloride (1143519-22-5) → rac-N-[(1R,2S)-2-amino-1,2-bis(4-chlorophenyl)-1-methylpropyl]-6-tert-butyl-4-ethoxynicotinamide

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at -10 ℃; for 0.833333h;

upstream raw materials:

para-chloroacetophenone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 939983-16-1 (2R,3S)-Rel-2,3-bis(4-chlorophenyl)-2,3-butanediaMine

Send

Send

Metric Ton KG G Pound L ML

Send

Send