9,10-Secochola-5,7,10(19),22-tetraen-24-ol, 24-cyclopropyl-1,3-bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]-, (1α,3β,5Z,7E,24S)- (9CI)

Base Information

Chemical Name:9,10-Secochola-5,7,10(19),22-tetraen-24-ol, 24-cyclopropyl-1,3-bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]-, (1α,3β,5Z,7E,24S)- (9CI)
CAS No.:910133-69-6
Molecular Formula:C₃₉H₆₈O₃Si₂
Molecular Weight:641.138
Hs Code.:
Mol file:910133-69-6.mol

Synonyms:Impurity of Calcipotriol;

Suppliers and Price of 9,10-Secochola-5,7,10(19),22-tetraen-24-ol, 24-cyclopropyl-1,3-bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]-, (1α,3β,5Z,7E,24S)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 8 raw suppliers

Chemical Property of 9,10-Secochola-5,7,10(19),22-tetraen-24-ol, 24-cyclopropyl-1,3-bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]-, (1α,3β,5Z,7E,24S)- (9CI)

Chemical Property:

PSA：38.69000
LogP:11.14960

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 9,10-Secochola-5,7,10(19),22-tetraen-24-ol, 24-cyclopropyl-1,3-bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]-, (1α,3β,5Z,7E,24S)- (9CI)

There total 80 articles about 9,10-Secochola-5,7,10(19),22-tetraen-24-ol, 24-cyclopropyl-1,3-bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]-, (1α,3β,5Z,7E,24S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 112849-26-0,134523-61-8,910133-69-6,910133-34-5
(1S,3R,3'R)-bis(tert-butyldimethylsilyloxy)-20(R)-(3'-cyclopropyl-3'-hydroxyprop-1'(E)-enyl)-9,10-secopregna-5(E),7(E),10⁽¹⁹⁾-triene

: 112849-27-1,134523-61-8,910133-69-6,910133-34-5
(1S,3R,3'S)-bis(tert-butyldimethylsilyloxy)-20(R)-(3'-cyclopropyl-3'-hydroxyprop-1'(E)-enyl)-9,10-secopregna-5(E),7(E),10⁽¹⁹⁾-triene

Guidance literature:: With sulfuric acid; In tetrahydrofuran; water; at 20 ℃; pH=1.7;

Reference yield: 33.0%

: 112849-17-9
1(S),3(R)-bis(tert-butyldimethylsilyloxy)-20(R)-(3’-cyclopropyl-3’-oxypropyl-1’(E)-enyl)-9,10-secopregna-5(E),7(E),10(19)-triene

: 112849-26-0,134523-61-8,910133-69-6,910133-34-5
(1S,3R,3'R)-bis(tert-butyldimethylsilyloxy)-20(R)-(3'-cyclopropyl-3'-hydroxyprop-1'(E)-enyl)-9,10-secopregna-5(E),7(E),10⁽¹⁹⁾-triene

: 112849-27-1,134523-61-8,910133-69-6,910133-34-5
(1S,3R,3'S)-bis(tert-butyldimethylsilyloxy)-20(R)-(3'-cyclopropyl-3'-hydroxyprop-1'(E)-enyl)-9,10-secopregna-5(E),7(E),10⁽¹⁹⁾-triene

Guidance literature:: With sodium tetrahydroborate; cerium(III) chloride; In methanol; further reag.: (S)-BINAL-H;
DOI:10.1016/S0040-4020(01)86903-9

Reference yield: 33.0%

: 112849-17-9
1(S),3(R)-bis(tert-butyldimethylsilyloxy)-20(R)-(3’-cyclopropyl-3’-oxypropyl-1’(E)-enyl)-9,10-secopregna-5(E),7(E),10(19)-triene

: 112849-26-0,134523-61-8,910133-69-6,910133-34-5
(1S,3R,3'R)-bis(tert-butyldimethylsilyloxy)-20(R)-(3'-cyclopropyl-3'-hydroxyprop-1'(E)-enyl)-9,10-secopregna-5(E),7(E),10⁽¹⁹⁾-triene

: 112849-27-1,134523-61-8,910133-69-6,910133-34-5
(1S,3R,3'S)-bis(tert-butyldimethylsilyloxy)-20(R)-(3'-cyclopropyl-3'-hydroxyprop-1'(E)-enyl)-9,10-secopregna-5(E),7(E),10⁽¹⁹⁾-triene

Guidance literature:: With sodium tetrahydroborate; cerium(III) chloride; In methanol; further reag.: (S)-BINAL-H;
DOI:10.1016/S0040-4020(01)86903-9