HE3235

Base Information

• Chemical Name: HE3235
• CAS No.: 183387-50-0
• Molecular Formula: C21H32O2
• Molecular Weight: 316.47800
• Mol file: 183387-50-0.mol

Synonyms:Apoptone;UNII-891O182ZP5;HE3235;

Chemical Property of HE3235

Chemical Property:

• PSA: 40.46000
• LogP: 3.75430
• Solubility.: ≤10mg/ml in ethanol;10mg/ml in DMSO;10mg/ml in dimethyl formamide

Purity/Quality:

98% ^*data from raw suppliers

HE-3235 ≥95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
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MSDS Files:

SDS file from LookChem

Useful:

• Description: HE-3235 is a synthetic adrenal hormone, an androstanediol analog, that acts as an androgen receptor antagonist. In an androgen receptor-dependent manner, it downregulates anti-apoptotic genes, while increasing the expression of pro-apoptotic genes, thus stimulating apoptosis. HE-3235 has been shown to inhibit androstenediol-dependent LNCaP cell tumor growth both in vitro (IC50 = 6 nM) and in xenograft models in vivo.

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