2,6-difluoro-4-propylphenol

Base Information

• Chemical Name: 2,6-difluoro-4-propylphenol
• CAS No.: 183244-98-6
• Molecular Formula: C₉H₁₀F₂O
• Molecular Weight: 172.175
• Mol file: 183244-98-6.mol

Synonyms:4-Propyl-2,6-difluorophenol;2,6-difluoro-4-propylphenol

Chemical Property of 2,6-difluoro-4-propylphenol

Chemical Property:

Purity/Quality:

95%, 99% ^*data from raw suppliers

2,6-Difluoro-4-propylphenol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-difluoro-4-propylphenol

There total 1 articles about 2,6-difluoro-4-propylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-propyl-3,5-difluorobenzene (183245-00-3) → 2,6-difluoro-4-propylphenol (183244-98-6)

Guidance literature:

1-propyl-3,5-difluorobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -40 - -35 ℃; for 1h; Inert atmosphere;

With Trimethyl borate; In tetrahydrofuran; hexane; at -40 - 20 ℃; for 0.5h; Inert atmosphere;

With dihydrogen peroxide; In water; at 40 ℃; for 6h; Inert atmosphere;

Reference yield:

2,6-difluoro-4-propylphenol (183244-98-6) + trans-4-(3,5-difluorophenyl)cyclohexyl methanol → 4-(3,5-difluorophenyl)cyclohexyl-(2,6-difluoro-4-propylphenyloxy)methane

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 - 23 ℃; for 0.166667h; Inert atmosphere;

Reference yield:

2,6-difluoro-4-propylphenol (183244-98-6) + 4-bromobenzenemethanol (873-75-6) → 4-[(2,6-difluoro-4-propylphenyloxy)methyl]bromobenzene

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at -10 - 20 ℃; for 3h;

upstream raw materials:

1-propyl-3,5-difluorobenzene

Refernces

• 1、 -. "COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE". Paragraph 0145; 0146. . Retrieved 2014/09/30.