5-(2-Naphthyl)-5-methyltetrahydrofuran-2-one

Base Information

Chemical Name:5-(2-Naphthyl)-5-methyltetrahydrofuran-2-one
CAS No.:21053-55-4
Molecular Formula:C15H14O2
Molecular Weight:226.275
Hs Code.:
NSC Number:122376
DSSTox Substance ID:DTXSID00298304
Nikkaji Number:J666.120C
ChEMBL ID:CHEMBL2134618
Mol file:21053-55-4.mol

Synonyms:NSC122376;MLS002707214;21053-55-4;CHEMBL2134618;DTXSID00298304;NSC-122376;SMR001574608

Suppliers and Price of 5-(2-Naphthyl)-5-methyltetrahydrofuran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 5-(2-Naphthyl)-5-methyltetrahydrofuran-2-one

Chemical Property:

Vapor Pressure:2.28E-07mmHg at 25°C
Boiling Point:423.2°Cat760mmHg
Flash Point:178.8°C
Density:1.172g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:226.099379685
Heavy Atom Count:17
Complexity:312

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CCC(=O)O1)C2=CC3=CC=CC=C3C=C2

Technology Process of 5-(2-Naphthyl)-5-methyltetrahydrofuran-2-one

There total 1 articles about 5-(2-Naphthyl)-5-methyltetrahydrofuran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21473-01-8
2-naphthalenylmagnesium bromide

: 539-88-8
4-oxopentanoic acid ethyl ester

: 21053-55-4
5-methyl-5-(naphthalen-2-yl)dihydrofuran-2(3H)-one

Guidance literature:: With diethyl ether;
DOI:10.1039/jr9410000376

Reference yield:

: 21053-55-4
5-methyl-5-(naphthalen-2-yl)dihydrofuran-2(3H)-one

: (+/-)-cis-4-(3,5-dinitrobenzamido)-1-methyl-1,2,3,4-tetrahydrophenanthrene

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd/BaSO₄ / methanol; tetrahydrofuran / 6 h / 2585.74 Torr

2: 43 percent / MeSO₃H / 1 h / 90 °C

3: NaCNBH₃; NH₄OAc / propan-2-ol / 44 h / Heating

4: aq. KOH / CH₂Cl₂ / 3 h

With potassium hydroxide; methanesulfonic acid; ammonium acetate; hydrogen; sodium cyanoborohydride; Pd-BaSO₄; In tetrahydrofuran; methanol; dichloromethane; isopropyl alcohol;
DOI:10.1016/S0040-4020(02)00307-1

Reference yield:

: 21053-55-4
5-methyl-5-(naphthalen-2-yl)dihydrofuran-2(3H)-one

: (+/-)-trans-4-(3,5-dinitrobenzamido)-1-methyl-1,2,3,4-tetrahydrophenanthrene

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd/BaSO₄ / methanol; tetrahydrofuran / 6 h / 2585.74 Torr

2: 43 percent / MeSO₃H / 1 h / 90 °C

3: NaCNBH₃; NH₄OAc / propan-2-ol / 44 h / Heating

4: aq. KOH / CH₂Cl₂ / 3 h

With potassium hydroxide; methanesulfonic acid; ammonium acetate; hydrogen; sodium cyanoborohydride; Pd-BaSO₄; In tetrahydrofuran; methanol; dichloromethane; isopropyl alcohol;
DOI:10.1016/S0040-4020(02)00307-1