(3aS,4R,6S,6aR)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol

Base Information

Chemical Name:(3aS,4R,6S,6aR)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
CAS No.:592533-90-9
Molecular Formula:C8H15NO3
Molecular Weight:173.21
Hs Code.:
Mol file:592533-90-9.mol

Synonyms:Ticagrelor Related Compound 2 ((3aS, 4R, 6S, 6aR)-6-Aminotetrahydro-2,2-Dimethyl-4H-Cyclopenta-1.3-dioxol-4-ol);

Suppliers and Price of (3aS,4R,6S,6aR)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3aS,4R,6S,6aR)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
10mg
$ 195.00

Crysdot
(3aS,4R,6S,6aR)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol 95+%
1g
$ 736.00

Chemenu
(3aS,4R,6S,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol 95%
1g
$ 695.00

Total 19 raw suppliers

Chemical Property of (3aS,4R,6S,6aR)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol

Chemical Property:

Boiling Point:288.0±40.0 oC (760 Torr)
PKA:14.03±0.60(Predicted)
Flash Point:128.0±27.3 oC
PSA：64.71000
Density:1.170±0.06 g/cm3 (20 oC 760 Torr)
LogP:0.29870

Purity/Quality:

97% ^*data from raw suppliers

(3aS,4R,6S,6aR)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (3aS,4R,6S,6aR)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol is used as a reagent to synthesize (3S,4R,5S)-(+)-3-amino-4,5-dihydroxycyclopentene for use as a chiral synthon toward carbocyclic nucleosides.

Technology Process of (3aS,4R,6S,6aR)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol

There total 10 articles about (3aS,4R,6S,6aR)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 592533-89-6
(1S,2R,6R,7R)-4,4-Dimethyl-3,5,8-trioxa-9-aza-tricyclo[5.2.1.0^2,6]decane

: 592533-90-9
(3aS,4R,6S,6aR)-6-Amino-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-ol

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 0.5h;
DOI:10.1016/S0040-4039(00)01668-3

Reference yield:

: 160167-61-3
(1R,4S)-N--2,3-oxazabicyclo<2.2.1>hept-5-ene

: 592533-90-9
(3aS,4R,6S,6aR)-6-Amino-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-ol

Guidance literature:: Multi-step reaction with 4 steps

1: OsO₄; NMO / tetrahydrofuran; H₂O

2: p-TsOH

3: NaBH₄ / methanol

4: H₂ / Pd/C / methanol

With sodium tetrahydroborate; osmium(VIII) oxide; N-methyl-2-indolinone; hydrogen; toluene-4-sulfonic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; water;
DOI:10.1016/S0040-4039(03)00973-0

Reference yield:

: [(S)-2-((1R,4S,5R,6R)-5,6-Dihydroxy-2-oxa-3-aza-bicyclo[2.2.1]hept-3-yl)-1-methyl-2-oxo-ethyl]-carbamic acid tert-butyl ester

: 592533-90-9
(3aS,4R,6S,6aR)-6-Amino-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-ol

Guidance literature:: Multi-step reaction with 3 steps

1: p-TsOH

2: NaBH₄ / methanol

3: H₂ / Pd/C / methanol

With sodium tetrahydroborate; hydrogen; toluene-4-sulfonic acid; palladium on activated charcoal; In methanol;
DOI:10.1016/S0040-4039(03)00973-0