2-Propanone, 1-(3-chlorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-

Base Information

Chemical Name:2-Propanone, 1-(3-chlorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
CAS No.:1038432-36-8
Molecular Formula:C15H23ClO2Si
Molecular Weight:298.885
Hs Code.:
Mol file:1038432-36-8.mol

Synonyms:(+/-)-1-[(tert-butyldimethylsilyl)oxy]-1-(3-chlorophenyl)propan-2-one

Suppliers and Price of 2-Propanone, 1-(3-chlorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Propanone, 1-(3-chlorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-

Chemical Property:

PSA：26.30000
LogP:4.99190

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Propanone, 1-(3-chlorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-

There total 7 articles about 2-Propanone, 1-(3-chlorophenyl)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1038432-24-4
(±)-methyl 2-{[(tert-butyldimethylsilyl)oxy](3-chlorophenyl)methyl}prop-2-enoate

: 1038432-36-8
(+/-)-1-[(tert-butyldimethylsilyl)oxy]-1-(3-chlorophenyl)propan-2-one

Guidance literature:: Multi-step reaction with 5 steps

1: water; lithium hydroxide / acetonitrile / 4 h / 50 - 60 °C

2: triethylamine / acetone / 0.08 h / 0 °C

3: sodium azide / acetone / 2 h / 20 °C

4: toluene / 2 h / Reflux; Inert atmosphere

5: water / 2 h / Reflux

With sodium azide; water; triethylamine; lithium hydroxide; In acetone; toluene; acetonitrile; 4: Curtius rearrangement;
DOI:10.1590/S0103-50532011000800022

Reference yield:

: 1038432-31-3
(+/-)-2-{[(tert-butyldimethylsilyl)oxy](3-chlorophenyl)methyl}prop-2-enoic acid

: 1038432-36-8
(+/-)-1-[(tert-butyldimethylsilyl)oxy]-1-(3-chlorophenyl)propan-2-one

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / acetone / 0.08 h / 0 °C

2: sodium azide / acetone / 2 h / 20 °C

3: toluene / 2 h / Reflux; Inert atmosphere

4: water / 2 h / Reflux

With sodium azide; water; triethylamine; In acetone; toluene; 3: Curtius rearrangement;
DOI:10.1590/S0103-50532011000800022

Reference yield:

: C₁₉H₂₇ClO₅Si

: 1038432-36-8
(+/-)-1-[(tert-butyldimethylsilyl)oxy]-1-(3-chlorophenyl)propan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: sodium azide / acetone / 2 h / 20 °C

2: toluene / 2 h / Reflux; Inert atmosphere

3: water / 2 h / Reflux

With sodium azide; water; In acetone; toluene; 2: Curtius rearrangement;
DOI:10.1590/S0103-50532011000800022