(5-BroMo-6-chloropyridin-3-yl)Methanol

Base Information

• Chemical Name: (5-BroMo-6-chloropyridin-3-yl)Methanol
• CAS No.: 904745-59-1
• Molecular Formula: C6H5BrClNO
• Molecular Weight: 222.467
• Hs Code.: 2933399090
• Mol file: 904745-59-1.mol

Synonyms:(5-BroMo-6-chloropyridin-3-yl)Methanol;(5-BroMo-6-chloro-3-pyridyl)Methanol

Chemical Property of (5-BroMo-6-chloropyridin-3-yl)Methanol

Chemical Property:

• PSA: 33.12000
• LogP: 1.98980

Purity/Quality:

97% ^*data from raw suppliers

(5-Bromo-6-chloro-3-pyridyl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (5-BroMo-6-chloropyridin-3-yl)Methanol

There total 2 articles about (5-BroMo-6-chloropyridin-3-yl)Methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

5-bromo-6-chloronicotinic acid (29241-62-1) → (5-bromo-6-chloropyridin-3-yl)methanol (904745-59-1)

Guidance literature:

5-bromo-6-chloronicotinic acid; With borane; In tetrahydrofuran; at 25 ℃; for 3h;

With hydrogenchloride; water; In tetrahydrofuran;

Reference yield:

5-bromo-6-chloro-3-pyridinecarboxylic acid methyl ester (78686-77-8) → (5-bromo-6-chloropyridin-3-yl)methanol (904745-59-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 - 20 ℃;

Reference yield: 63.0%

(5-bromo-6-chloropyridin-3-yl)methanol (904745-59-1) → 3-bromo-2-chloro-5-(chloromethyl)pyridine (904745-60-4)

Guidance literature:

With thionyl chloride; In dichloromethane; at 25 ℃; for 5h;

upstream raw materials:

5-bromo-6-chloronicotinic acid

5-bromo-6-chloro-3-pyridinecarboxylic acid methyl ester

Downstream raw materials:

3-bromo-2-chloro-5-(chloromethyl)pyridine

3-bromo-2-chloro-5-formylpyridine

3-bromo-5-(bromomethyl)-2-chloropyridine