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7-Hydroxy Mitragynine

Base Information Edit
  • Chemical Name:7-Hydroxy Mitragynine
  • CAS No.:174418-82-7
  • Molecular Formula:C23H30N2O5
  • Molecular Weight:414.502
  • Hs Code.:
  • Mol file:174418-82-7.mol
7-Hydroxy Mitragynine

Synonyms:Mitragynine hydroxyindolenine;7α-Hydroxy-7H-mitragynine;Methyl (E)-2-[(2S,3S,7aS,12bS)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate;7-Hydroxy Mitragynine;9-Methoxycorynantheidine hydroxyindolenine;

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Chemical Property of 7-Hydroxy Mitragynine Edit
Chemical Property:
  • Boiling Point:567.4±50.0 °C(Predicted) 
  • PKA:12.20±0.60(Predicted) 
  • Flash Point:2℃ 
  • PSA:80.59000 
  • Density:1.29±0.1 g/cm3(Predicted) 
  • LogP:2.16610 
  • Storage Temp.:-20?C Freezer 
Purity/Quality:
Safty Information:
  • Pictogram(s): F,T 
  • Hazard Codes:F,T 
  • Statements: 11-23/24/25-39/23/24/25 
  • Safety Statements: 16-36/37-45 
MSDS Files:

SDS file from LookChem

Useful:
  • Description 7-Hydroxymitragynine is a terpenoid indole alkaloid from the plant Mitragyna speciosa, It is a minor constituent of this plant (Ponglux et al., 1994). 7-Hydroxymitragynine exhibited a higher potency than mitragynine in the guinea-pig ileum test and a high affinity for A-opioid receptors in binding assays (Takayama et al., 2002).
  • Uses A metabolite of Mitragynine. Along with mitragynine, 7-Hydroxymitragynine is an active alkaloid found in the plant Mitragynine speciosa, commonly known as Kratom. The compound possesses opioid agonistic activity with a potentcy 30- and 17-fold higher than that of mitragynine and morphine, respectively.
Technology Process of 7-Hydroxy Mitragynine

There total 23 articles about 7-Hydroxy Mitragynine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium hydroxide; In methanol; at 0 ℃; for 2h;
DOI:10.1021/jm010576e
Guidance literature:
With bis-[(trifluoroacetoxy)iodo]benzene; In tetrahydrofuran; water; at 2 ℃; for 3h; Temperature; Inert atmosphere;