CyclohexylMethyl N-tosyloxycarbaMate

Base Information

• Chemical Name: CyclohexylMethyl N-tosyloxycarbaMate
• CAS No.: 869111-41-1
• Molecular Formula: C15H21NO5S
• Molecular Weight: 327.401
• Mol file: 869111-41-1.mol

Synonyms:CyclohexylMethyl N-tosyloxycarbaMate;tert-butyl tosyloxycarbaMate;[[(4-Methylphenyl)sulfonyl]oxy]carbamic acid cyclohexylmethyl ester

Chemical Property of CyclohexylMethyl N-tosyloxycarbaMate

Chemical Property:

• Melting Point: 89-91℃
• PSA: 90.08000
• LogP: 4.39350

Purity/Quality:

99% ^*data from raw suppliers

Cyclohexylmethyltosyloxycarbamate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CyclohexylMethyl N-tosyloxycarbaMate

There total 2 articles about CyclohexylMethyl N-tosyloxycarbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

cyclohexylmethyl N-hydroxycarbamate (869111-30-8) + p-toluenesulfonyl chloride (98-59-9) → cyclohexylmethyl N-tosyloxycarbamate (869111-41-1)

Guidance literature:

With triethylamine; In diethyl ether; at 20 ℃; for 12h;

DOI:10.1021/ja0552850

Reference yield:

cyclohexylmethyl alcohol (100-49-2) → cyclohexylmethyl N-tosyloxycarbamate (869111-41-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 2 h / 20 °C

1.2: 80 percent / hydroxylamine hydrochloride / pyridine / 6 h / 20 °C

2.1: 88 percent / triethylamine / diethyl ether / 12 h / 20 °C

With triethylamine; In tetrahydrofuran; diethyl ether;

DOI:10.1021/ja0552850

Reference yield: 84.0%

cyclohexylmethyl N-tosyloxycarbamate (869111-41-1) → 3-oxa-1-azaspiro[4.5]decan-2-one (81467-34-7)

Guidance literature:

With dirhodium(II) tetrakis(triphenylacetate); potassium carbonate; In dichloromethane; at 25 ℃; for 6h;

DOI:10.1021/ja0552850

upstream raw materials:

cyclohexylmethyl N-hydroxycarbamate

p-toluenesulfonyl chloride

cyclohexylmethyl alcohol

Downstream raw materials:

3-oxa-1-azaspiro[4.5]decan-2-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 869111-41-1 CyclohexylMethyl N-tosyloxycarbaMate

Send

Send

Metric Ton KG G Pound L ML

Send

Send