5-NAPHTHALEN-1-YLMETHYL-[1,3,4]THIADIAZOL-2-YLAMINE

Base Information

• Chemical Name: 5-NAPHTHALEN-1-YLMETHYL-[1,3,4]THIADIAZOL-2-YLAMINE
• CAS No.: 383130-61-8
• Molecular Formula: C13H11N3S
• Molecular Weight: 241.31
• Hs Code.: 2934999090
• Mol file: 383130-61-8.mol

Synonyms:TIMTEC-BB SBB011811;5-NAPHTHALEN-1-YLMETHYL-[1,3,4]THIADIAZOL-2-YLAMINE;5-(1-NAPHTHYLMETHYL)-1,3,4-THIADIAZOL-2-AMINE;5-(1-naphthalenylmethyl)-1,3,4-Thiadiazol-2-amine

Chemical Property of 5-NAPHTHALEN-1-YLMETHYL-[1,3,4]THIADIAZOL-2-YLAMINE

Chemical Property:

• Boiling Point: 481.9±38.0 °C(Predicted)
• PKA: 3.40±0.50(Predicted)
• PSA: 80.04000
• Density: 1.332±0.06 g/cm3(Predicted)
• LogP: 3.44550

Purity/Quality:

98%min ^*data from raw suppliers

5-Naphthalen-1-ylmethyl-[1,3,4]thiadiazol-2-ylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-NAPHTHALEN-1-YLMETHYL-[1,3,4]THIADIAZOL-2-YLAMINE

There total 1 articles about 5-NAPHTHALEN-1-YLMETHYL-[1,3,4]THIADIAZOL-2-YLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

naphth-1-yl acetic acid (86-87-3) + thiosemicarbazide (79-19-6) → 5-(naphthalen-1-ylmethyl)-1,3,4-thiadiazol-2-amine (383130-61-8)

Guidance literature:

With sulfuric acid; at 60 - 70 ℃; for 8h;

DOI:10.1016/j.molstruc.2021.130174

Reference yield:

5-(naphthalen-1-ylmethyl)-1,3,4-thiadiazol-2-amine (383130-61-8) + 4-(bromoacetyl)toluene (619-41-0) → 6-(4-methylphenyl)-2-(naphthalen-1-ylmethyl)imidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:

With potassium carbonate; In ethanol; for 12h;

DOI:10.1016/j.molstruc.2021.130174

Reference yield:

5-(naphthalen-1-ylmethyl)-1,3,4-thiadiazol-2-amine (383130-61-8) + 2-Bromo-4'-methoxyacetophenone (2632-13-5) → 6-(4-methoxyphenyl)-2-(naphthalen-1-ylmethyl)imidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:

With potassium carbonate; In ethanol; for 12h;

DOI:10.1016/j.molstruc.2021.130174

upstream raw materials:

naphth-1-yl acetic acid

thiosemicarbazide