2-BIPHENYL-4-YL-5-(TRIFLUOROMETHYL)-1,3,4-OXADIAZOL

Base Information

• Chemical Name: 2-BIPHENYL-4-YL-5-(TRIFLUOROMETHYL)-1,3,4-OXADIAZOL
• CAS No.: 887267-97-2
• Molecular Formula: C₁₅H₉F₃N₂O
• Molecular Weight: 290.244
• Hs Code.: 2934999090

Synonyms:2-BIPHENYL-4-YL-5-(TRIFLUOROMETHYL)-1,3,4-OXADIAZOL;4-[5-(Trifluoromethyl)-1,3,4-oxadiazol-2-yl]biphenyl

Chemical Property of 2-BIPHENYL-4-YL-5-(TRIFLUOROMETHYL)-1,3,4-OXADIAZOL

Chemical Property:

• PSA: 38.92000
• LogP: 4.42240

Purity/Quality:

99% ^*data from raw suppliers

2-([1,1'-Biphenyl]-4-yl)-5-(trifluoromethyl)-1,3,4-oxadiazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
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MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BIPHENYL-4-YL-5-(TRIFLUOROMETHYL)-1,3,4-OXADIAZOL

There total 1 articles about 2-BIPHENYL-4-YL-5-(TRIFLUOROMETHYL)-1,3,4-OXADIAZOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

biphenyl-4-acetaldehyde (92-91-1) → 2-([1,1'-biphenyl]-4-yl)-5-(trifluoromethyl)-1,3,4-oxadiazole (887267-97-2)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine; selenium(IV) oxide / 16 h / 110 °C

2: dichloromethane / 36 h / 20 °C / Schlenk technique; Inert atmosphere; Irradiation

With pyridine; selenium(IV) oxide; In dichloromethane;

DOI:10.1021/acs.orglett.1c03603

upstream raw materials:

biphenyl-4-acetaldehyde

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