Methyl 2-((benzo[d]thiazol-2-ylthio)methyl)benzoate

Base Information

• Chemical Name: Methyl 2-((benzo[d]thiazol-2-ylthio)methyl)benzoate
• CAS No.: 1213268-08-6
• Molecular Formula: C16H13NO2S2
• Molecular Weight: 315.41
• Hs Code.: 2934200090
• Mol file: 1213268-08-6.mol

Synonyms:Methyl 2-((benzo[d]thiazol-2-ylthio)methyl)benzoate

Chemical Property of Methyl 2-((benzo[d]thiazol-2-ylthio)methyl)benzoate

Chemical Property:

• PSA: 92.73000
• LogP: 4.37520

Purity/Quality:

≥99% ^*data from raw suppliers

Methyl2-((benzo[d]thiazol-2-ylthio)methyl)benzoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 2-((benzo[d]thiazol-2-ylthio)methyl)benzoate

There total 1 articles about Methyl 2-((benzo[d]thiazol-2-ylthio)methyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl 2-bromomethylbenzoate (2417-73-4) + 2-Mercaptobenzothiazole (149-30-4,118090-09-8) → methyl 2-{(benzo[d]thiazol-2-ylthio)methyl}benzoate (1213268-08-6)

Guidance literature:

With potassium carbonate; In acetone; for 10h; Reflux;

DOI:10.1002/ejoc.201601264

Reference yield: 86.0%

methyl 2-{(benzo[d]thiazol-2-ylthio)methyl}benzoate (1213268-08-6) → methyl 2-{(benzo[d]thiazol-2-ylsulfonyl)methyl}-benzoate (1213268-11-1)

Guidance literature:

With sodium tungstate (VI) dihydrate; dihydrogen peroxide; In methanol; at 0 - 20 ℃; for 6h;

DOI:10.1002/ejoc.200901012

Reference yield:

methyl 2-{(benzo[d]thiazol-2-ylthio)methyl}benzoate (1213268-08-6) → methyl (E)-2-(2-(5-((tert-butoxycarbonyl)amino)-2,2-dimethyl-1,3-dioxan-5-yl)vinyl)benzoate (1213268-19-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: dihydrogen peroxide; sodium tungstate (VI) dihydrate / methanol / 0 - 20 °C

2.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / 0 °C

2.2: 2.5 h / 20 °C

With sodium tungstate (VI) dihydrate; dihydrogen peroxide; sodium hydride; In methanol; N,N-dimethyl-formamide;

DOI:10.1002/ejoc.201601264

upstream raw materials:

methyl 2-bromomethylbenzoate

2-Mercaptobenzothiazole

Downstream raw materials:

methyl 2-{(benzo[d]thiazol-2-ylsulfonyl)methyl}-benzoate

2-[(Z)-(S)-2-(1,4-Dioxa-spiro[4.5]dec-2-yl)-vinyl]-benzoic acid methyl ester

2-[(E)-(S)-2-(1,4-Dioxa-spiro[4.5]dec-2-yl)-vinyl]-benzoic acid methyl ester

methyl (Z)-2-(hept-1-en-1-yl)benzoate