ButanaMide, 3-aMino-N-Methyl-4-(phenylthio)-, (3R)-

Base Information

• Chemical Name: ButanaMide, 3-aMino-N-Methyl-4-(phenylthio)-, (3R)-
• CAS No.: 1012059-97-0
• Molecular Formula: C11H16N2OS
• Molecular Weight: 224.327
• Hs Code.: 2930909090
• Mol file: 1012059-97-0.mol

Synonyms:ButanaMide, 3-aMino-N-Methyl-4-(phenylthio)-, (3R)-

Chemical Property of ButanaMide, 3-aMino-N-Methyl-4-(phenylthio)-, (3R)-

Chemical Property:

• PSA: 83.91000
• LogP: 2.78270
• Storage Temp.: 2-8°C

Purity/Quality:

≥99% ^*data from raw suppliers

(R)-3-Amino-N-methyl-4-(phenylthio)butanamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ButanaMide, 3-aMino-N-Methyl-4-(phenylthio)-, (3R)-

There total 1 articles about ButanaMide, 3-aMino-N-Methyl-4-(phenylthio)-, (3R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

(R)-benzyl 4-(methylamino)-4-oxo-1-(phenylthio)butan-2-ylcarbamate (1012059-96-9) → (R)-3-amino-N-methyl-4-(phenylthio)butanamide (1012059-97-0)

Guidance literature:

(R)-benzyl 4-(methylamino)-4-oxo-1-(phenylthio)butan-2-ylcarbamate; With hydrogen bromide; In water; acetic acid; at 80 ℃; for 4h;

With potassium hydroxide; In water; pH=12;

Reference yield: 55.0%

4-fluoro-3-nitrobenzenesulfonamide (406233-31-6) + (R)-3-amino-N-methyl-4-(phenylthio)butanamide (1012059-97-0) → (R)-N-methyl-3-(2-nitro-4-sulfamoylphenylamino)-4-(phenylthio)butanamide (1012059-98-1)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 4h;

upstream raw materials:

(R)-benzyl 4-(methylamino)-4-oxo-1-(phenylthio)butan-2-ylcarbamate

Downstream raw materials:

(R)-N-methyl-3-(2-nitro-4-sulfamoylphenylamino)-4-(phenylthio)butanamide

Refernces