DL-Homoserine

Base Information

• Chemical Name: DL-Homoserine
• CAS No.: 1927-25-9
• Molecular Formula: C4H9NO3
• Molecular Weight: 119.12
• Hs Code.: 29225090
• European Community (EC) Number: 217-661-8
• NSC Number: 206298,206251,37755
• UNII: JN0F9A0SSO
• DSSTox Substance ID: DTXSID80862365
• Nikkaji Number: J1.207F
• Wikipedia: Homoserine
• Wikidata: Q27113920
• Mol file: 1927-25-9.mol

Synonyms:Homoserine;Homoserine L-isomer;L isomer of Homoserine;L-isomer of Homoserine

Chemical Property of DL-Homoserine

Chemical Property:

• Appearance/Colour: off-white crystalline solid
• Vapor Pressure: 6.16E-07mmHg at 25°C
• Melting Point: 188-189 °C
• Refractive Index: 1.51
• Boiling Point: 368.7 °C at 760 mmHg
• PKA: 2.21±0.10(Predicted)
• Flash Point: 176.8 °C
• PSA: 83.55000
• Density: 1.312 g/cm³
• LogP: -0.51900
• Storage Temp.: Store at RT.
• Solubility.: Water (Sparingly)
• Water Solubility.: soluble
• XLogP3: -4.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 119.058243149
• Heavy Atom Count: 8
• Complexity: 83.4

Purity/Quality:

99% ^*data from raw suppliers

DL-Homoserine ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CO)C(C(=O)O)N
• Uses: D,L-Homoserine (cas# 1927-25-9) is a compound useful in organic synthesis.

Technology Process of DL-Homoserine

There total 27 articles about DL-Homoserine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(3S)-(3-amino-3-carboxypropyl)dimethylsulfonium iodide (3493-11-6) → DL-Homoserine (1927-25-9,119736-88-8)

Guidance literature:

With water; sodium hydrogencarbonate; pH=2 - 5; Reflux;

Reference yield: 26.0%

α-amino-γ-bromobutyric acid hydrobromide (76338-90-4) → DL-Homoserine (1927-25-9,119736-88-8)

Guidance literature:

With sodium hydroxide; In methanol; for 3h; Ambient temperature;

Reference yield:

avenic acid A (76224-57-2,120964-18-3) → DL-Homoserine (1927-25-9,119736-88-8) + malic acid (617-48-1,78644-42-5) + aspartic Acid (617-45-8,25608-40-6,27881-03-4,32505-46-7,52526-39-3)

Guidance literature:

With potassium permanganate; Product distribution;

DOI:10.1016/S0040-4039(00)77410-7

upstream raw materials:

2-amino-4-phenoxybutanoic acid

2-(N,N-dibenzylamino)-4-hydroxybutyric acid lactone

2-amino-4-chlorobutyric acid

4-hydroxy-2-phenylhydrazono-butyric acid

Downstream raw materials:

2-tert-butoxycarbonylamino-4-hydroxy-butyric acid benzyl ester

2-(tert-butoxycarbonylamino)-4-hydroxy-butanoic acid

N-benzoylhomoserine lactone

5-(β-bromoethyl)hydantoin

Refernces

• 1、 -. "Microorganisms and methods for the biosynthesis of butadiene". . . Retrieved 2017/09/02.
• 2、 -. "MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF BUTADIENE". Page/Page column. . Retrieved 2014/06/23.