1α,2β,3α,5β-Cyclohexanetetrol

Base Information

• Chemical Name: 1α,2β,3α,5β-Cyclohexanetetrol
• CAS No.: 53585-08-3
• Molecular Formula: C₆H₁₂O₄
• Molecular Weight: 148.159
• Mol file: 53585-08-3.mol

Synonyms:1α,2β,3α,5β-Cyclohexanetetrol

Chemical Property of 1α,2β,3α,5β-Cyclohexanetetrol

Chemical Property:

• Melting Point: 178 - 180 °C
• Boiling Point: 297.1±40.0 °C(Predicted)
• PKA: 13.88±0.70(Predicted)
• PSA: 80.92000
• Density: 1.569±0.06 g/cm3(Predicted)
• LogP: -1.77620

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1α,2β,3α,5β-Cyclohexanetetrol

There total 3 articles about 1α,2β,3α,5β-Cyclohexanetetrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+/-)-4c,6t-Dibrom-1r,2c,3c,5t-tetrahydroxy-cyclohexan (6090-94-4,89673-82-5) → cyclohexanetetrol-(1r,2c,3c,5t) (3877-36-9,53585-08-3,64396-74-3,136936-97-5)

Guidance literature:

With ion-exchange resin + form>; hydrogen; nickel; In water;

DOI:10.1021/jo01031a061

Reference yield:

O1,O2;O3,O4-diisopropyliden-5,6-anhydro-allo-inositol (744209-88-9) → cyclohexanetetrol-(1r,2c,3c,5t) (3877-36-9,53585-08-3,64396-74-3,136936-97-5)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) HBr, AcOH, (ii) Ac₂O, (iii) HCl, EtOH

2: H₂, ion-exchange resin + form> / Raney-Ni / H₂O

With ion-exchange resin + form>; hydrogen; nickel; In water;

DOI:10.1021/jo01031a061

Reference yield:

(+/-)-4c,6t-dibromo-cyclohexane-1r,2t,3c,5t-tetraol (6090-94-4,89673-82-5) → cyclohexane-1r,2t,3c,5t-tetraol (53585-08-3)

Guidance literature:

With water; nickel; Hydrogenation;

DOI:10.1021/ja01638a024

upstream raw materials:

(+/-)-4c,6t-dibromo-cyclohexane-1r,2t,3c,5t-tetraol

(+/-)-4c,6t-Dibrom-1r,2c,3c,5t-tetrahydroxy-cyclohexan

O¹,O²;O³,O⁴-diisopropyliden-5,6-anhydro-allo-inositol

Downstream raw materials:

Tetra-N,O-acetyl-4,6-didesoxystreptamin

1r,2t,3c,5t-tetrakis-benzoyloxy-cyclohexane