4-(5-Methylpyridin-2-yl)morpholine

Base Information

Chemical Name:4-(5-Methylpyridin-2-yl)morpholine
CAS No.:251101-37-8
Molecular Formula:C10H14N2O
Molecular Weight:178
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40572554
Wikidata:Q82460938
Mol file:251101-37-8.mol

Synonyms:4-(5-methylpyridin-2-yl)morpholine;251101-37-8;Morpholine, 4-(5-methyl-2-pyridinyl)-;SCHEMBL46309;DTXSID40572554;AKOS016844532;J-513601

Suppliers and Price of 4-(5-Methylpyridin-2-yl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(5-Methylpyridin-2-yl)morpholine 95+%
10g
$ 442.00

Crysdot
4-(5-Methylpyridin-2-yl)morpholine 95+%
5g
$ 344.00

Chemenu
4-(5-methylpyridin-2-yl)morpholine 95%
5g
$ 325.00

Chemenu
4-(5-methylpyridin-2-yl)morpholine 95%
10g
$ 417.00

American Custom Chemicals Corporation
4-(5-METHYLPYRIDIN-2-YL)MORPHOLINE 95.00%
5MG
$ 495.01

Alichem
4-(5-Methylpyridin-2-yl)morpholine
10g
$ 378.00

Alichem
4-(5-Methylpyridin-2-yl)morpholine
5g
$ 296.80

Total 9 raw suppliers

Chemical Property of 4-(5-Methylpyridin-2-yl)morpholine

Chemical Property:

PSA：25.36000
LogP:1.29160
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:178.110613074
Heavy Atom Count:13
Complexity:157

Purity/Quality:

97% ^*data from raw suppliers

4-(5-Methylpyridin-2-yl)morpholine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN=C(C=C1)N2CCOCC2

Technology Process of 4-(5-Methylpyridin-2-yl)morpholine

There total 5 articles about 4-(5-Methylpyridin-2-yl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 110-91-8,99108-56-2
morpholine

: 2369-19-9
2-fluoro-5-methylpyridine

: 251101-37-8
4-(5-methylpyridin-2-yl)morpholine

Guidance literature:: morpholine; With n-butyllithium; In tetrahydrofuran; hexane; at 0 - 20 ℃; for 0.25h; Inert atmosphere;

2-fluoro-5-methylpyridine; In tetrahydrofuran; hexane; at 0 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jacs.7b11710

Reference yield: 78.3%

: 110-89-4
piperidine

: 3510-66-5
2-Bromo-5-methylpyridine

: 251101-37-8
4-(5-methylpyridin-2-yl)morpholine

Guidance literature:: With C₃₀H₂₅BrN₃PPdS; potassium carbonate; In iso-butanol; at 100 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.tetlet.2012.12.070

Reference yield: 78.0%

: 132546-81-7
methyl 6-morpholinonicotinate

: 251101-37-8
4-(5-methylpyridin-2-yl)morpholine

Guidance literature:: With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; 1,1,3,3-Tetramethyldisiloxane; potassium tert-butylate; 1,3-bis(cyclohexyl)imidazolium tetrafluoroborate; In toluene; at 110 ℃; for 10h; Glovebox; Inert atmosphere; Sealed tube;
DOI:10.1021/jacs.0c02405