Cyclopenta[c]pyrrole-1-carboxylic acid, 2-[(2S)-2-aMino-3,3-diMethyl-1-oxobutyl]octahydro-, 1,1-diMethylethyl ester, (1S,3aR,6aS)-

Base Information

Chemical Name:Cyclopenta[c]pyrrole-1-carboxylic acid, 2-[(2S)-2-aMino-3,3-diMethyl-1-oxobutyl]octahydro-, 1,1-diMethylethyl ester, (1S,3aR,6aS)-
CAS No.:926276-16-6
Molecular Formula:C18H32N2O3
Molecular Weight:324.464
Hs Code.:
Mol file:926276-16-6.mol

Synonyms:Cyclopenta[c]pyrrole-1-carboxylic acid, 2-[(2S)-2-aMino-3,3-diMethyl-1-oxobutyl]octahydro-, 1,1-diMethylethyl ester, (1S,3aR,6aS)-;(1S,3aR,6aS)-2-[(2S)-2-Amino-3,3-dimethyl-1-oxobutyl]octahydrocyclopenta[c]pyrrole-1-carboxylic acid tert-butyl ester;Cyclopenta[c]pyrrole-1-carboxylic acid, 2-[(2S)-2-3,3-dimethyl-1-oxobutyl]octahydro-,1,1-dimethylethyl ester,(1S,3aR,6aS)-;(1S,3aR,6aS)-tert-butyl 2-((S)-2-amino-3,3-dimethylbutanoyl)octahydrocyclopenta[c]pyrrole-1-carboxylate

Suppliers and Price of Cyclopenta[c]pyrrole-1-carboxylic acid, 2-[(2S)-2-aMino-3,3-diMethyl-1-oxobutyl]octahydro-, 1,1-diMethylethyl ester, (1S,3aR,6aS)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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American Custom Chemicals Corporation
2-[(2S)-2-3,3-DIMETHYL-1-OXOBUTYL]OCTAHYDRO-,1,1-DIMETHYLETHYL ESTER,(1S,3AR,6AS)-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID 95.00%
5MG
$ 500.46

Total 7 raw suppliers

Chemical Property of Cyclopenta[c]pyrrole-1-carboxylic acid, 2-[(2S)-2-aMino-3,3-diMethyl-1-oxobutyl]octahydro-, 1,1-diMethylethyl ester, (1S,3aR,6aS)-

Chemical Property:

PSA：72.63000
Density:1.072
LogP:2.96680

Purity/Quality:

99%, ^*data from raw suppliers

2-[(2S)-2-3,3-DIMETHYL-1-OXOBUTYL]OCTAHYDRO-,1,1-DIMETHYLETHYL ESTER,(1S,3AR,6AS)-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclopenta[c]pyrrole-1-carboxylic acid, 2-[(2S)-2-aMino-3,3-diMethyl-1-oxobutyl]octahydro-, 1,1-diMethylethyl ester, (1S,3aR,6aS)-

There total 1 articles about Cyclopenta[c]pyrrole-1-carboxylic acid, 2-[(2S)-2-aMino-3,3-diMethyl-1-oxobutyl]octahydro-, 1,1-diMethylethyl ester, (1S,3aR,6aS)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62965-37-1
(S)-2-(((benzyloxy)carbonyl)amino)-3,3-dimethylbutanoic acid dicyclohexylammonium salt

: 926276-16-6
(1S,3aR,6aS)tert-butyl 2-((S)-2-amino-3,3-dimethylbutanoyl)-octahydrocyclopenta[c]pyrrole-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: tert-butyl methyl ether; sulfuric acid / water / 1 h / 20 °C / Inert atmosphere

2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 2.23 h / 0 - 5 °C

2.2: 1.88 h / 0 - 20 °C

3.1: hydrogen / 10 wt% Pd(OH)2 on carbon / Isopropyl acetate / 1 h / 20 °C / 760.05 Torr / Inert atmosphere

With tert-butyl methyl ether; sulfuric acid; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 10 wt% Pd(OH)2 on carbon; In Isopropyl acetate; water; N,N-dimethyl-formamide;

Reference yield:

: 926276-16-6
(1S,3aR,6aS)tert-butyl 2-((S)-2-amino-3,3-dimethylbutanoyl)-octahydrocyclopenta[c]pyrrole-1-carboxylate

: 69901-75-3
(S)-[[(benzyloxy)carbonyl]amino](cyclohexyl)acetic acid

: 926276-17-7
(1S,3aR,6aS)-t-butyl 2-((S)-2-((S)-2-(benzyloxycarbonylamino)-2-cyclohexylacetamido)-3,3-dimethylbutanoyl)octahydrocyclopenta[c]pyrrole-1-carboxylate

Guidance literature:: (1S,3aR,6aS)tert-butyl 2-((S)-2-amino-3,3-dimethylbutanoyl)-octahydrocyclopenta[c]pyrrole-1-carboxylate; (S)-[[(benzyloxy)carbonyl]amino](cyclohexyl)acetic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In Isopropyl acetate; water; N,N-dimethyl-formamide; at 0 - 25 ℃; for 22h;

With 4-methyl-morpholine; histamine dichloride; In Isopropyl acetate; water; N,N-dimethyl-formamide; at 20 ℃; for 0.25 - 0.333333h;

With potassium carbonate; In Isopropyl acetate; water; N,N-dimethyl-formamide; for 0.5h; Product distribution / selectivity;