5-(Piperazin-1-yl)pyrimidine

Base Information

Chemical Name:5-(Piperazin-1-yl)pyrimidine
CAS No.:202135-70-4
Molecular Formula:C8H12N4
Molecular Weight:164.211
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00452929
Nikkaji Number:J1.570.564G
Wikidata:Q82273832
Mol file:202135-70-4.mol

Synonyms:5-(Piperazin-1-yl)pyrimidine;202135-70-4;5-piperazin-1-ylpyrimidine;Pyrimidine, 5-(1-piperazinyl)-;1-(5-Pyrimidinyl)piperazine;SCHEMBL1914594;DTXSID00452929;AKOS011779025;CS-0271891;EN300-1255928;A879777

Suppliers and Price of 5-(Piperazin-1-yl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-(Piperazin-1-yl)pyrimidine 95+%
1g
$ 455.00

Chemenu
5-(Piperazin-1-yl)pyrimidine 95%
1g
$ 430.00

American Custom Chemicals Corporation
5-(PIPERAZIN-1-YL)PYRIMIDINE 95.00%
5MG
$ 498.27

Alichem
5-(Piperazin-1-yl)pyrimidine
1g
$ 433.83

Total 6 raw suppliers

Chemical Property of 5-(Piperazin-1-yl)pyrimidine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:328.095°C at 760 mmHg
PKA:8.61±0.10(Predicted)
Flash Point:152.227°C
PSA：41.05000
Density:1.139g/cm³
LogP:0.28000
Storage Temp.:2-8°C(protect from light)
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:164.106196400
Heavy Atom Count:12
Complexity:127

Purity/Quality:

97% ^*data from raw suppliers

5-(Piperazin-1-yl)pyrimidine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C2=CN=CN=C2

Technology Process of 5-(Piperazin-1-yl)pyrimidine

There total 2 articles about 5-(Piperazin-1-yl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 634468-96-5
tert-butyl 4-(pyrimidin-5-yl)piperazine-1-carboxylate

: 202135-70-4
5-(piperazin-1-yl)pyrimidine

Guidance literature:: tert-butyl 4-(pyrimidin-5-yl)piperazine-1-carboxylate; With Amberlyst(R) 15; In dichloromethane; at 20 ℃;

With ammonium hydroxide; In methanol; at 20 ℃; for 1.5h;
DOI:10.1016/j.tetlet.2006.02.047

Reference yield: 9.0%

: 110-85-0
piperazine

: 4595-59-9
5-bromopyrimidine

: 202135-70-4
5-(piperazin-1-yl)pyrimidine

Guidance literature:: With dichlorobis(tri-O-tolylphosphine)palladium; sodium t-butanolate; In various solvent(s); at 169 ℃; for 24h;
DOI:10.1248/cpb.49.1314